Buy Voltarol
Voltarol

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Voltarol (Diclofenac) is a potent non-steroidal anti-inflammatory medication used to alleviate pain and reduce inflammation. It addresses symptoms of various conditions, including rheumatoid arthritis and acute injuries. By inhibiting inflammatory enzymes, it helps patients regain mobility and general comfort.


Ingredient
Category
Availability
In Stock
Delivery Time
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Diclofenac
Reference Brand
Voltarol Pain-eze
Manufacturer
Haleon
Product Form
Tablet, Gel, Patch, Suppository
Regulatory Classification
OTC
Primary Category
Pain Relief, Anti-inflammatory
Product Category
Musculo-Skeletal System, Anti-inflammatory and Antirheumatic Products, Acetic Acid Derivatives
Pharmacological Class
NSAIDs
Manufacturer Description
A powerful anti-inflammatory available in various forms to treat pain, swelling, and stiffness.
Mechanism of Action
Voltarol contains diclofenac, which works by inhibiting enzymes (COX-1 and COX-2) that produce prostaglandins. Prostaglandins are chemicals in the body that signal pain and cause inflammation. By reducing their production, the medication relieves pain and reduces swelling.
Route of Administration
Topical
Onset Time
1-3 hours (Oral), 1 hour (Topical)
Duration
8-12 hours
Contraindications
Asthma triggered by aspirin or NSAIDs, Active stomach ulcers, Severe heart failure, Last trimester of pregnancy, Kidney or liver failure
Severe Adverse Events
Gastrointestinal bleeding, Severe allergic reactions, Heart attack or stroke risk (with high-dose oral use), Jaundice
Common Side Effects
Skin rash (topical), Itching, Redness at application site
Uncommon Side Effects
Indigestion, Headache, Dizziness, Stomach ache
Drug Interactions
Aspirin, Warfarin, Lithium, Methotrexate, Other NSAIDs like Ibuprofen
Pregnancy Safety Warnings
Avoid during the first and second trimesters unless essential; strictly contraindicated in the third trimester.
Age Restrictions
Gel versions generally for ages 14+; Tablets vary by strength
Storage Guidelines
Store below 30°C. Do not freeze gels.
Related Products
Ibuprofen, Naproxen, Felbinac

Voltarol FAQ

Can I take Voltarol with other NSAIDs for stronger pain relief?

Concurrent use of multiple NSAIDs increases the risk of gastrointestinal bleeding and kidney injury without providing additional analgesic benefit. It is generally advised to avoid combining diclofenac with other NSAIDs unless a specialist explicitly recommends it.

Is Voltarol safe for people with asthma?

Diclofenac can trigger bronchospasm in a small subset of patients with aspirin-sensitive asthma. Those with a known NSAID-induced asthma flare should avoid Voltarol and discuss alternative analgesics with their clinician.

What should I do if I experience mild stomach upset after taking Voltarol?

Taking the tablet with food or a full glass of water can reduce irritation. If symptoms persist, contact your healthcare provider, who may suggest a proton-pump inhibitor or an alternative pain medication.

Does Voltarol appear different in various UK regions?

Brand-name Voltarol tablets are typically white, round, and imprinted with “VOL 100”. Generic diclofenac tablets may vary in colour, shape, and imprint depending on the manufacturer, but the strength (100 mg) remains the same.

Can Voltarol be detected in a workplace drug test?

Diclofenac is not a controlled substance and is not screened for in standard workplace drug testing panels. However, some occupational health programs may request a full medication list for safety assessments.

Is there a risk of kidney damage with short-term Voltarol use?

Short courses (≤ 7 days) of diclofenac at recommended doses are generally safe for people with normal kidney function. Individuals with pre-existing renal disease should be monitored closely, even for brief therapy.

How does Voltarol compare to ibuprofen for joint pain?

Both are NSAIDs, but diclofenac (Voltarol) is often considered more potent on a per-milligram basis for inflammatory joint conditions. Individual response varies, and side-effect profiles differ; a clinician can help determine the most suitable option.

Can I travel internationally with Voltarol tablets?

Yes, provided you carry the medication in its original packaging with a prescription label. Some countries require a doctor’s note for NSAIDs, so check the destination’s import regulations before travel.

What inactive ingredients are in Voltarol tablets?

Typical excipients include lactose, microcrystalline cellulose, and magnesium stearate. Patients with specific allergies (e.g., lactose intolerance) should verify the exact formulation with their pharmacist.

Will taking Voltarol affect my blood test results?

Diclofenac can slightly elevate liver enzymes (ALT, AST) and may affect renal function markers (creatinine). If you are undergoing routine blood work, inform the laboratory or your physician about recent NSAID use.

Voltarol: What Is It?

Voltarol is a brand-name medication that contains the active ingredient diclofenac. It belongs to the pain-relief therapeutic class and is available in the United Kingdom as an oral pill of 100 mg strength. The product is prescription-only (POM) and is regulated by the Medicines and Healthcare products Regulatory Agency (MHRA).

How Voltarol Works in the Body

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It reduces pain and inflammation by inhibiting the cyclo-oxygenase (COX) enzymes, primarily COX-2, which are needed to produce prostaglandins-chemicals that promote inflammation, fever, and pain. By lowering prostaglandin levels, diclofenac decreases the sensation of pain and limits swelling at the site of injury.

  • Onset of action: Usually within 30-60 minutes after oral intake.
  • Peak effect: Approximately 2-4 hours.
  • Duration: Effects can last 6-8 hours, depending on individual metabolism.

Diclofenac is well absorbed from the gastrointestinal tract, with an oral bioavailability of about 50 %. It is extensively bound to plasma proteins (≈99 %) and is metabolised in the liver, mainly via CYP2C9, before being excreted in the urine.

Conditions Treated by Voltarol

In the UK, diclofenac tablets such as Voltarol are licensed for short-term relief of:

  • Mild to moderate musculoskeletal pain (e.g., sprains, strains, back pain)
  • Osteoarthritis pain when other therapies are insufficient
  • Rheumatoid arthritis flares (as part of a broader treatment plan)

The medication is intended for adult patients who require additional pain control beyond simple analgesics like paracetamol.

Patient Suitability and Contraindications

Who Should Use Voltarol?

  • Adults with acute or chronic inflammatory pain where an NSAID is appropriate
  • Patients without a history of serious gastrointestinal, cardiovascular, or renal disease

Absolute Contraindications

  • Known hypersensitivity to diclofenac, other NSAIDs, or any excipients in the tablet
  • History of gastrointestinal bleeding or ulceration related to NSAID use
  • Severe heart failure (NYHA Class III/IV)
  • Third-trimester pregnancy (diclofenac may affect fetal cardiovascular development)

Relative Contraindications

  • Mild to moderate renal impairment (dose adjustment may be required)
  • Liver disease (monitor liver function tests)
  • Controlled hypertension (NSAIDs can raise blood pressure)
  • Use in elderly patients (increased risk of adverse events)

Special Populations

  • Pregnancy & lactation: Diclofenac is generally avoided in the third trimester. Use during the first two trimesters only if the benefit outweighs the risk, and always under medical supervision. Diclofenac is excreted in breast milk in small amounts; breastfeeding mothers should discuss risks with a healthcare professional.
  • Pediatric use: Not licensed for children under 18 years for the oral tablet form.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Gastro-intestinal discomfort (indigestion, nausea) - commonly reported
  • Headache - mild and transient for most users
  • Dizziness - may occur, especially when standing quickly

Serious Adverse Events

  • Upper gastrointestinal bleeding or perforation - rare but potentially life-threatening; seek immediate medical attention if you experience black stools or severe abdominal pain.
  • Cardiovascular events (heart attack, stroke) - risk increases with long-term use or in patients with existing heart disease.
  • Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) - discontinue and seek urgent care if rash spreads or blisters develop.

Drug Interactions

  • Major: Concurrent use with other NSAIDs, anticoagulants (e.g., warfarin), or selective serotonin reuptake inhibitors (SSRIs) can markedly increase bleeding risk.
  • Moderate: ACE inhibitors, diuretics, and lithium may have altered plasma levels when combined with diclofenac; monitoring is advised.
  • Enzyme-based interactions: Strong CYP2C9 inhibitors (e.g., fluconazole) can raise diclofenac concentrations; dose adjustment may be necessary.

Patients should always provide a complete medication list to their prescriber before starting Voltarol.

Food and Lifestyle Interactions

  • Food: Taking the tablet with food can lessen stomach irritation, but does not significantly affect overall absorption.
  • Alcohol: Excessive alcohol use heightens the risk of gastrointestinal bleeding; limit intake while on diclofenac.
  • Driving: Diclofenac is not known to impair cognition or coordination, but dizziness can occur; use caution if you feel unsteady.

Dosing and Administration Guidelines

Standard dosing (based on the 100 mg tablet):

  • The usual adult regimen involves one 100 mg tablet taken one to three times daily, as directed by a healthcare professional.
  • The total daily dose should not exceed 300 mg unless explicitly advised by a prescriber.

Special population adjustments

  • Renal impairment: For moderate renal dysfunction, a reduced dose (e.g., 50 mg once daily) may be considered.
  • Hepatic impairment: Start with the lowest effective dose and monitor liver enzymes.
  • Elderly patients: Initiate therapy at the lowest effective dose and assess tolerability.

Administration tips

  • Swallow the tablet whole with a full glass of water.
  • Do not crush or chew the tablet, as this may increase gastrointestinal irritation.
  • Store at room temperature, away from moisture and direct sunlight.

Missed dose: If you forget a dose, take it as soon as you remember unless it is near the time of your next scheduled dose. Do not double up.

Overdose: Symptoms may include severe nausea, vomiting, abdominal pain, and dizziness. Seek emergency medical help immediately; treatment is supportive and may involve activated charcoal.

Discontinuation: Abrupt stopping is generally safe, but if you have been using high doses for an extended period, discuss a tapering plan with your prescriber to minimise rebound pain.

Monitoring and Follow-Up

  • Renal function: Serum creatinine and eGFR should be checked before initiating therapy and periodically thereafter in at-risk patients.
  • Liver enzymes: Baseline ALT/AST testing is advisable, especially for long-term use.
  • Blood pressure: Monitor regularly, as NSAIDs can raise systolic and diastolic pressures.

Patients should contact their healthcare provider if they experience persistent stomach pain, unexplained swelling, sudden weight gain, or signs of bleeding.

Storage and Handling

  • Keep the bottle tightly closed and store at 20-25 °C (68-77 °F).
  • Protect from excessive heat, moisture, and direct sunlight.
  • Do not use the medication after the expiry date printed on the pack.
  • For safe disposal, return unused tablets to a pharmacy or follow local NHS guidelines for medication waste.

Medication-Specific Glossary

Cyclo-oxygenase (COX) inhibition
The process by which diclofenac blocks the COX enzymes, reducing prostaglandin synthesis and thereby diminishing pain and inflammation.
Bioavailability
The proportion of an orally administered drug that reaches systemic circulation unchanged; for diclofenac tablets, this is roughly 50 %.
Prostaglandins
Lipid compounds that mediate inflammation, pain, and fever; they are the primary target of NSAIDs like diclofenac.
CYP2C9
A liver enzyme that metabolises diclofenac; inhibitors of this enzyme can increase diclofenac levels in the blood.
Black-box warning
The strongest FDA/EMA safety alert, indicating that diclofenac carries a risk of serious cardiovascular and gastrointestinal events when used long-term or in high-risk patients.

Medical Disclaimer

This article provides educational information about Voltarol and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Information for Voltarol is sourced from established medical standards and updated frequently. It is provided for general guidance and should be confirmed with a healthcare professional before use.
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