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Orlistat Medication Information Leaflet

Common Use

Orlistat is commonly used for weight management and to reduce the risk of regaining weight already lost. It is used in combination with a low-calorie diet and exercise to help people lose weight.

Classification

Orlistat is classified as a lipase inhibitor. It works in the intestines, where it blocks some of the fat one eats from being absorbed and can help people lose weight.

Generic Ingredient

Orlistat's generic compound is also known as Tetrahydrolipstatin. It is available in the UK as a prescription medication for weight management.

Certification Information

Orlistat has been approved for use in many countries, including the UK, for the management of obesity and weight control.

Known Alternatives in UK

Some known alternatives to Orlistat for weight management in the UK may include prescription medications such as Phentermine and Liraglutide.

Clinical Use

Orlistat is used clinically to help people achieve significant weight loss. It can be prescribed to individuals with a body mass index (BMI) of 30 or more, or 28 or more if associated with other risk factors.

Spectrum Of Activity

The primary activity of Orlistat is to reduce the absorption of dietary fats. It does not affect the absorption of carbohydrates or proteins.

Drug interaction

Orlistat may interact with certain medications such as cyclosporine, levothyroxine, and anticoagulants. Patients should consult their healthcare provider before using Orlistat if they are taking other medications.

Dosage and Directions

The typical dosage of Orlistat is 120mg to be taken three times a day with meals, or as directed by a healthcare professional. It should be used in conjunction with a reduced-calorie and low-fat diet.

Contraindications and Precautions

Orlistat should not be used by individuals who have malabsorption syndrome or cholestasis. Precautions should be taken in individuals with a history of kidney stones, pancreatitis, or gallbladder problems.

Possible side effect

Common side effects of Orlistat can include oily spotting, gas, and frequent bowel movements. Users may also experience difficulty controlling bowel movements. These side effects are often related to the fat-blocking action of the medication.

Missed dose and Overdose

If a dose of Orlistat is missed, it can be taken within one hour of the meal. A missed dose should be skipped if the meal is skipped or does not contain fat. Overdosing on Orlistat may lead to increased side effects, and medical attention should be sought if an overdose is suspected.

Storage

Orlistat should be stored at room temperature, away from moisture and heat. It should be kept out of reach of children.

Known Non-standard Use

In some cases, Orlistat may be used off-label for the management of obesity in individuals who have not been able to achieve significant weight loss through diet and exercise alone.

Special Cases

Special caution should be exercised when prescribing Orlistat to individuals with a history of eating disorders, as it may exacerbate the psychological aspects of these conditions.

Patient Considerations

Patients considering the use of Orlistat should discuss with their healthcare provider and receive guidance on how to incorporate a reduced-calorie diet and exercise into their weight loss plan.

Breastfeeding and Pregnancy

Orlistat is not recommended for use during pregnancy or while breastfeeding.

Possible Risks

The use of Orlistat may be associated with an increased risk of gastrointestinal adverse effects such as steatorrhea, fecal incontinence, and abdominal pain. It is important for individuals using Orlistat to be aware of these potential risks.

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Orlistat FAQ

How does Orlistat work?

Orlistat works by reducing the absorption of fat in the body, thus helping in weight loss.

What are the side effects of Orlistat?

Side effects of Orlistat may include oily spotting, gas with discharge, oily or fatty stools, and an urgent need to have a bowel movement.

Can Orlistat be taken with other medications?

It's important to consult a healthcare professional before combining Orlistat with other medications to avoid any potential interactions.

How long does it take for Orlistat to show results?

Individual results may vary, but generally, noticeable weight loss may be observed within the first 3 months of using Orlistat.

What is the recommended dosage for Orlistat?

The typical dosage for Orlistat is one 120mg capsule taken with each of the three main meals per day.

Is Orlistat suitable for vegetarians or vegans?

Orlistat capsules are suitable for vegetarians and vegans as they do not contain any animal-derived ingredients.

Are there any dietary restrictions while taking Orlistat?

It's recommended to follow a well-balanced, reduced-calorie diet while taking Orlistat to achieve the best results.

Is Orlistat safe for long-term use?

Long-term use of Orlistat should be done under the supervision of a healthcare professional to monitor any potential effects on vitamin absorption.

Can Orlistat be used during pregnancy or breastfeeding?

Orlistat is not recommended for use during pregnancy or while breastfeeding, as its effects on the developing baby are not yet fully known.

What should I do if I miss a dose of Orlistat?

If a dose of Orlistat is missed, it can be taken within an hour of the missed meal. However, it should not be doubled up to make up for the missed dose.

Does Orlistat require a prescription?

Orlistat is available in both prescription and over-the-counter forms, depending on the dosage strength.

Can Orlistat be used by individuals with diabetes?

Individuals with diabetes should consult their healthcare provider before using Orlistat, as it may affect blood sugar control.

What lifestyle changes should accompany the use of Orlistat?

In addition to taking Orlistat, incorporating regular physical activity and adopting healthy eating habits are important for successful weight management.

How should Orlistat capsules be stored?

Orlistat capsules should be stored in a cool, dry place, away from direct heat and light.

Are there any age restrictions for using Orlistat?

Orlistat is typically recommended for use in adults aged 18 and older and should not be given to children or adolescents without medical supervision.