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sinemet

$32.10

  • Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
  • Prescription: Included
  • Availability: In Stock

Sinemet is a popular treatment for Parkinson's disease that works by increasing dopamine levels in the brain

Table of contents

Buying Sinemet Online

Can You Buy Sinemet in UK?

Yes, Sinemet is available in UK, provided you have a valid prescription from a certified healthcare professional or an regulated online pharmacy. For affordable alternatives, you may choose to purchase Sinemet through our online pharmacy. We work with trusted global providers, ensuring adherence to UK's strict import regulations.

Ordering Sinemet via our online pharmacy is straightforward and secure. Your prescription will be processed promptly, and all imports meet the legal requirements set by UK. This ensures you have affordable and stress-free access to your medication.

Why You Can Import Sinemet into UK

In line with MHRA guidelines, importing Sinemet for personal use is allowed, provided the quantity is within approved limits and accompanied by a valid prescription, which we can help facilitate. This opens up economical options, including reliable generic alternatives.

How to Save Money on Sinemet in UK

  • Select non-branded Carbidopa-plus-levodopa to significantly reduce costs while maintaining the same therapeutic benefits.
  • Compare prices from reliable online pharmacies to secure the best deals.
  • Utilise our online drugstore for competitive international pricing and special offers.

Why Choose Generic Sinemet?

Generic Carbidopa-plus-levodopa is bioequivalent to its branded counterpart, providing equivalent therapeutic effects at a much lower price. It's an smart choice for budget-savvy customers seeking economical treatment options.

How to Get Budget-Friendly Sinemet Refills

Refilling your Sinemet prescription is hassle-free and cost-effective with our service. Enjoy a 10% discount on every refill by reordering through your account. We ensure that refills are both simple and budget-friendly.

Exclusive Benefits for UK Customers

For customers in UK, we offer dedicated solutions to ensure seamless access to Sinemet. Our platform fully complies with the MHRA’s import regulations, giving you peace of mind while saving time and money. Take advantage of exclusive shipping discounts and expedited delivery across the UK, including all major cities (Manchester, Leeds, Birmingham, London, Glasgow, Liverpool).

Sinemet Buyer and Patient Handbook in UK

What is Sinemet?

Sinemet is a well-known medication primarily used to treat Parkinson's disease and Parkinsonism. It comprises a combination of Levodopa and Carbidopa. Levodopa is converted to dopamine in the brain, a neurotransmitter that helps control movement. Carbidopa is included to prevent Levodopa from converting into dopamine before reaching the brain, maximizing its effects while minimizing side effects. Sinemet is certified and prescribed by healthcare professionals across the UK.

Who Should Use Sinemet?

Sinemet is suitable for adults diagnosed with Parkinson's disease, particularly those who are experiencing motor symptoms like tremors and rigidity. It may be prescribed to the elderly as they often are more prone to this neurological condition. Pediatric use is rare and should be assessed by a specialist, as it is not typically recommended for children.

How Does It Work?

Once ingested, Sinemet’s components work together to increase dopamine levels in the brain. This boost helps to relieve symptoms associated with low dopamine, improving motor skills and coordination. For many patients, using Sinemet can enhance daily activities like driving, working, and exercising by reducing muscle stiffness and improving overall mobility. However, be aware that initial doses might induce drowsiness, so caution is advised.

Dosage and Administration

The typical starting dose of Sinemet varies but often begins with 100 mg of Levodopa combined with 25 mg of Carbidopa, taken three to four times daily. Dosage may be adjusted based on individual response and side effects.

  • Missed Dose: If you miss a dose, take it as soon as you remember, unless it’s nearly time for your next dose. In that case, skip the missed dose – do not double up.
  • Overdose: In the event of an overdose, seek immediate medical attention. Symptoms might include uncontrolled movements or severe nausea.

Special considerations include:

  • Elderly: Starting with a lower dose might be advised due to potential increased sensitivity.
  • Kids: Dosage should be determined by a healthcare professional.
  • Liver and Kidney Issues: Consult your doctor, as dosage adjustments may be necessary.

Lifestyle and Dietary Recommendations

To enhance the effectiveness of Sinemet:

  • Maintain a balanced diet rich in fruits and vegetables.
  • Stay hydrated.
  • Avoid high-protein meals close to your medication time, as proteins can compete with Levodopa absorption.

Precautions and Warnings

  • Regular monitoring by a healthcare professional is crucial.
  • Inform your doctor if you have any history of heart problems, breathing issues, or glaucoma.
  • Avoid alcohol consumption, which can amplify side effects.

Potential Side Effects

Common Side Effects:

  • Nausea
  • Dizziness
  • Dry mouth

Less Common Side Effects:

  • Fatigue
  • Changes in mood
  • Confusion

Serious Side Effects:

  • Uncontrolled movements
  • Severe allergic reactions
  • Mental health changes (hallucinations, severe depression)

Drug Interactions

Medication Name Interaction
Antipsychotic drugs May decrease the effectiveness of Sinemet
High protein diets Can hinder Levodopa absorption
Iron supplements May interfere with absorption

Who Should Avoid This Medication?

Individuals with hypersensitivity to Levodopa or Carbidopa should avoid using Sinemet. It’s also not recommended for those with narrow-angle glaucoma, severe liver disease, or certain types of skin cancer.

Storage Instructions

Store Sinemet at room temperature, away from moisture and heat. Keep it in its original packaging to protect from light. Ensure it’s out of reach of children.

Why Choose Sinemet?

Sinemet stands out in Parkinson's treatment for its effectiveness at managing motor symptoms and greatly improving quality of life. Compared to alternatives, it combines Levodopa and Carbidopa efficiently, reducing side effects associated with early conversion to dopamine. Sinemet may also be considered off-label for certain conditions like Restless Leg Syndrome.

Sinemet Alternatives

Name Description Comparisons
Stalevo Combines Levodopa, Carbidopa, and Entacapone More comprehensive but may have higher side effects.
Comtan Entacapone used with Levodopa Similar effect on dopamine, but only for boost and not standalone.
Mirapex Pramipexole, a dopamine agonist Different mechanism but can be used for Parkinson's symptoms.

Sinemet FAQ

What is Sinemet primarily used for?

Sinemet is used for managing symptoms of Parkinson's disease and certain types of Parkinsonism.

Can I take Sinemet if I'm pregnant?

Consult your healthcare provider, as medications during pregnancy should be evaluated for risks and benefits.

How quickly can I expect to see results from Sinemet?

Many patients see an improvement in motor symptoms within a few weeks, but individual response may vary.

Can I drink alcohol while taking Sinemet?

Alcohol can increase side effects and should be consumed cautiously or avoided.

Is Sinemet the same as generic Levodopa?

No, Sinemet includes Carbidopa, which improves Levodopa’s efficacy and reduces side effects.

How long can I stay on Sinemet?

Your doctor will evaluate your long-term needs; they typically adjust dosages based on effectiveness and side effects.

Are there special storage instructions for Sinemet?

Yes, store it at room temperature away from moisture and light.

Does Sinemet cause weight gain?

Weight changes can vary among individuals; it is plausible but not a common effect.

Can I stop taking Sinemet suddenly?

Do not stop abruptly without consulting your doctor, as it may lead to severe symptoms.

What should I do if I feel drowsy after taking Sinemet?

Avoid activities that require full concentration, like driving, until you understand how Sinemet affects you.

Glossary

Levodopa
A precursor to dopamine, used in Parkinson's treatment to increase brain dopamine levels.
Carbidopa
A medication that prevents Levodopa from converting to dopamine outside the brain, reducing side effects.
Dopamine
A neurotransmitter crucial for coordinating movement and regulating mood; deficits are linked to Parkinson's disease.
Parkinsonism
A term for a group of neurological disorders that exhibit Parkinson-like symptoms.
Antipsychotic
Medications used to treat psychiatric disorders, which may interfere with Sinemet's effectiveness.
Hydration
The process of maintaining adequate fluid balance in the body, crucial for overall health, especially when on medications like Sinemet.
Allergic Reactions
An immune response to medications that can be severe and requires immediate medical attention.
Absorption
The process by which drugs enter the bloodstream; can be affected by food and other medications.
Tremor
Involuntary muscle shaking often associated with Parkinson's disease.
Mental Health Changes
Refers to alterations in emotion or cognition, which can affect well-being and quality of life.

References

Sinemet Properties

  • Conditions To Treat: Parkinson's disease
  • Clinical Use: Dopamine precursor and decarboxylase inhibitor used to treat Parkinson's disease
  • Spectrum Of Activity: Increases dopamine levels in the brain, improving motor symptoms in patients with Parkinson's disease
  • Mechanism Of Action: Levodopa is converted to dopamine in the brain, while carbidopa inhibits the breakdown of levodopa outside the brain
  • Length Of Use: Long term, used as maintenance therapy to manage symptoms of Parkinson's disease
  • Recommended Dosage: Start with 25mg of carbidopa/100mg of levodopa three times daily
  • Side Effects: Nausea, vomiting, hallucinations, dyskinesia

How to Purchase Sinemet | Carbidopa Plus Levodopa on our Website

Purchasing Sinemet | Carbidopa Plus Levodopa from our online pharmacy is simple. Just select the required dosage and quantity of pills above. The price of your choice will update automatically. Next, click the Add to Cart button to add the chosen amount to your cart. You can either continue shopping for more pills or head to the checkout. At the Checkout, complete the payment process using our secure and dedicated payment gateway.

Sinemet / Carbidopa-plus-levodopa pills are made from high-quality generic compounds and are subject to strict quality control measures under WHO and The Medicines and Healthcare products Regulatory Agency (MHRA) standards. However, Sinemet pills are shipped from outside of UK due to prescriptions issued overseas.

Reviews

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Sinemet

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Information provided by Maryam Abdullahi-Mahdi. Reviewed by Prof. Vijay Sangar