Orlistat is a medication used to help people lose weight by preventing the absorption of fats from the diet. It works by inhibiting the action of enzymes in the gut which digest fats. This in turn reduces the number of calories absorbed, aiding weight loss.

Orlistat FAQ


How does Orlistat work?

Orlistat works in the intestines, where it blocks some of the fat you eat from being absorbed.

The recommended dosage of Orlistat is 120 mg taken three times a day with meals, or as directed by a healthcare professional.

Is Orlistat suitable for everyone?

Orlistat may not be suitable for everyone, such as pregnant or breastfeeding women, and those with certain digestive disorders. It is important to consult a healthcare professional before use.

How long does it take to see results with Orlistat?

Individual results may vary, but some people may start to see weight loss results within 2 weeks of starting Orlistat.

What are the potential side effects of Orlistat?

Common side effects of Orlistat include oily spotting, gas with discharge, urgent need to have a bowel movement, oily or fatty stools, and an increased number of bowel movements.

Can I buy Orlistat over the counter?

Orlistat is available over the counter in lower dosage, while higher dosage requires a prescription. Always check with a pharmacist or healthcare professional.

How long can Orlistat be taken for?

Orlistat can be taken for as long as necessary, provided it is well tolerated and the individual continues to benefit from its use.

Can Orlistat be taken with other medications?

It is important to consult a healthcare professional before taking Orlistat alongside other medications, as it may interact with certain drugs.

Is Orlistat a safe option for weight loss?

When used as directed and under the guidance of a healthcare professional, Orlistat can be a safe and effective option for weight loss.

Is Orlistat suitable for long-term weight management?

Orlistat can be used for long-term weight management, especially when combined with a healthy diet and regular physical activity.

Are there any dietary restrictions when taking Orlistat?

There are no specific dietary restrictions when taking Orlistat, but it is recommended to follow a healthy, balanced diet for best results.

How should Orlistat be stored?

Orlistat should be stored at room temperature, away from moisture and heat. Keep it out of the reach of children and pets.

Can Orlistat cause vitamin deficiencies?

Due to its mechanism of action, Orlistat can potentially reduce the absorption of some vitamins. It is advisable to supplement with a daily multivitamin containing fat-soluble vitamins.

Is Orlistat effective for everyone trying to lose weight?

Individual responses to Orlistat may vary. It is important to combine its use with a calorie-controlled diet and exercise for best results.

What is the difference between Alli and Xenical?

Alli and Xenical both contain the active ingredient Orlistat, but at different strengths. Alli is available over the counter, whereas Xenical requires a prescription.

Is Orlistat FDA approved?

Yes, Orlistat is approved by the FDA for weight management in overweight and obese adults.

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Information provided by Maryam Abdullahi-Mahdi. Reviewed by Prof. Vijay Sangar