Graft-versus-host disease FAQ
What is Graft-versus-host disease (GVHD)?
GVHD is a medical condition that can develop after a stem cell or bone marrow transplant.
What are the symptoms of GVHD?
The symptoms may include skin rash, abdominal pain, diarrhea, and jaundice.
How is GVHD diagnosed?
GVHD can be diagnosed through physical examination and tests such as blood tests and skin biopsies.
What are the treatment options for GVHD?
Treatment may include corticosteroids, immunosuppressants, and photopheresis.
Can GVHD be prevented?
There are measures to lower the risk, such as careful matching of donor and recipient and the use of immunosuppressants.
Is GVHD life-threatening?
In severe cases, GVHD can be life-threatening. Early detection and treatment are crucial.
Can GVHD affect multiple organs?
Yes, GVHD can affect the skin, liver, gastrointestinal tract, and other organs.
Are there support groups for GVHD patients?
Yes, there are support groups and online communities that provide valuable support and information for GVHD patients.
Is GVHD common after a transplant?
GVHD is a potential complication of stem cell or bone marrow transplants, but not everyone who undergoes these procedures will develop GVHD.
What is the role of immunosuppressants in GVHD treatment?
Immunosuppressants are used to suppress the immune response that causes GVHD.
Can GVHD recur after successful treatment?
Yes, GVHD can recur even after successful treatment. Regular monitoring is important.
What lifestyle changes can help manage GVHD?
Managing stress, following a healthy diet, and avoiding infections can help in managing GVHD.
What are the long-term effects of GVHD?
Long-term effects may include skin changes, liver and kidney damage, and an increased risk of infections.
Can GVHD affect children as well?
Yes, GVHD can affect children who have undergone stem cell or bone marrow transplants.
Are there ongoing research efforts for GVHD treatments?
Yes, there are ongoing research efforts aimed at developing new treatments and improving outcomes for GVHD patients.
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Information provided by Maryam Abdullahi-Mahdi. Reviewed by Mr. Matthew Liew