Tacrolimus is an immunosuppressive drug used after organ transplant to lower the risk of organ rejection. It belongs to a class of medications called calcineurin inhibitors and works by suppressing the immune system. Tacrolimus is available in the form of capsules and injections.

Tacrolimus FAQ


What is tacrolimus used for?

Tacrolimus is used to prevent rejection of heart, kidney, liver, or lung transplants.

How does tacrolimus work?

Tacrolimus works by decreasing the activity of the immune system to prevent it from attacking the transplanted organ.

What are the common side effects of tacrolimus?

Common side effects include tremor, headache, high blood pressure, kidney problems, and increased risk of infections.

Can I take tacrolimus with other medications?

It's important to consult a healthcare professional before taking tacrolimus with other medications to avoid potential interactions.

How should tacrolimus be taken?

Tacrolimus is usually taken twice daily, 12 hours apart. It's important to take it at the same times each day.

What should I do if I miss a dose of tacrolimus?

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.

Is tacrolimus available as a generic medication?

Yes, tacrolimus is available as a generic medication.

Can tacrolimus be used during pregnancy?

Tacrolimus may harm an unborn baby. It's important to discuss the risks and benefits with a healthcare professional if you are pregnant or planning to become pregnant while using tacrolimus.

Can tacrolimus be used in children?

Tacrolimus can be used in children who have had a liver or kidney transplant, usually over 6 months old.

How often do I need to have my blood tested while taking tacrolimus?

Blood tests are required regularly to monitor kidney and liver function, as well as the amount of tacrolimus in the blood.

What should I avoid while taking tacrolimus?

Avoid consuming grapefruit or grapefruit juice while taking tacrolimus, as it can increase the risk of side effects.

Is tacrolimus safe for long-term use?

Tacrolimus can be used long-term if prescribed by a healthcare professional. Regular monitoring is essential to assess its impact on the body.

Can tacrolimus cause skin problems?

In some cases, tacrolimus can cause skin problems such as acne, itching, or increased hair growth. It's important to consult a healthcare professional if you experience any skin-related issues.

Can tacrolimus cause diabetes?

Long-term use of tacrolimus may increase the risk of developing diabetes. Monitoring blood sugar levels is essential while taking this medication.

Can I drive while taking tacrolimus?

Tacrolimus may cause dizziness and tremors, which can affect the ability to drive or operate machinery. It's important to assess individual response before engaging in such activities.

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Information provided by Maryam Abdullahi-Mahdi. Reviewed by Prof. Vijay Sangar