Primary Biliary Cholangitis, formerly known as Primary Biliary Cirrhosis, is a chronic liver disease that affects the bile ducts. It can lead to liver damage and scarring if not treated.

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Primary Biliary Cholangitis FAQ


What is Primary Biliary Cholangitis?

Primary Biliary Cholangitis is an autoimmune disease that affects the liver's bile ducts, leading to reduced bile flow and potential liver damage.

What are the symptoms of Primary Biliary Cholangitis?

Symptoms include fatigue, itching, abdominal pain, and jaundice. However, some individuals may have no symptoms in the early stages.

How is Primary Biliary Cholangitis diagnosed?

Diagnosis involves blood tests to check liver function and specific antibodies, as well as imaging tests and a liver biopsy in some cases.

What are the treatment options for Primary Biliary Cholangitis?

The primary treatment is medication to slow the progression of the disease and manage symptoms. Liver transplant may be considered in advanced cases.

Is Primary Biliary Cholangitis curable?

Primary Biliary Cholangitis is not curable, but treatment can help manage the condition and slow its progression, especially if diagnosed early.

What is the role of Ursodeoxycholic Acid in treating PBC?

Ursodeoxycholic Acid is a primary medication used to treat Primary Biliary Cholangitis. It helps to improve liver function and slow the progression of the disease.

Can diet and lifestyle changes help manage Primary Biliary Cholangitis?

A balanced diet and regular exercise can help support overall health, but they cannot cure the condition. Patients should consult with their doctor for specific recommendations.

Are there any support groups for people with Primary Biliary Cholangitis?

Yes, there are support groups and online communities where individuals with PBC can connect, share experiences, and find valuable support and information.

Can pregnancy affect Primary Biliary Cholangitis?

Pregnancy can pose risks for women with PBC. It's essential for women with this condition to discuss family planning and pregnancy-related concerns with their healthcare provider.

What should one know about managing medications for Primary Biliary Cholangitis?

Patients should take their prescribed medications as directed by their healthcare provider, report any side effects, and attend regular follow-up appointments for monitoring.

Is it safe to take over-the-counter medications with PBC?

Patients should always consult their healthcare provider before taking any over-the-counter or prescription medications, as some may have adverse effects on the liver or interact with PBC medications.

How can one cope with the emotional impact of having Primary Biliary Cholangitis?

It's normal to experience a range of emotions when living with a chronic condition. Seeking support from loved ones, healthcare professionals, or therapists and counselors can be beneficial.

What are the potential complications of untreated Primary Biliary Cholangitis?

Untreated PBC can lead to liver damage, cirrhosis, and eventually, liver failure. Regular medical care and adherence to treatment are crucial to prevent these complications.

Can exercise help individuals with Primary Biliary Cholangitis?

Regular exercise can contribute to overall well-being. However, individuals with PBC should discuss their exercise routine with a healthcare provider to ensure it aligns with their specific needs.

Is it possible to live a normal life with Primary Biliary Cholangitis?

With appropriate treatment and lifestyle adjustments, many individuals with PBC can live fulfilling lives. It's important to adhere to medical advice and seek support when needed.

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Information provided by Maryam Abdullahi-Mahdi. Reviewed by Mr. Matthew Liew