Zollinger-Ellison Syndrome is a rare condition where tumors form in the pancreas or duodenum, leading to overproduction of stomach acid. Symptoms may include severe abdominal pain, diarrhea, and ulcers. Treatment focuses on reducing acid production, typically through medication or surgery.

Zollinger-Ellison Syndrome FAQ


What is Zollinger-Ellison Syndrome?

Zollinger-Ellison Syndrome is a rare condition where tumors in the pancreas or duodenum cause excessive production of stomach acid.

What are the symptoms of Zollinger-Ellison Syndrome?

Symptoms may include abdominal pain, diarrhea, heartburn, bloating, and ulcers that are slow to heal.

How is Zollinger-Ellison Syndrome diagnosed?

Diagnosis is often made through blood tests to measure gastrin levels, imaging studies, and endoscopy.

What are the treatment options for Zollinger-Ellison Syndrome?

Treatment typically involves medications to reduce stomach acid production, as well as surgery to remove tumors if necessary.

Is Zollinger-Ellison Syndrome curable?

While there is no cure, symptoms can be effectively managed with proper treatment to control acid production.

Can diet affect Zollinger-Ellison Syndrome?

Yes, certain foods can trigger symptoms, so it's important to avoid spicy, fatty, or acidic foods.

What are the long-term complications of Zollinger-Ellison Syndrome?

Left untreated, the condition can lead to serious complications like severe ulcers, bleeding, and even gastrointestinal cancer.

Can Zollinger-Ellison Syndrome be hereditary?

In a few cases, there may be a genetic predisposition, but in most instances, the condition is not inherited.

Is Zollinger-Ellison Syndrome life-threatening?

If left untreated, the complications of Zollinger-Ellison Syndrome can be life-threatening, making prompt diagnosis and treatment essential.

How does stress affect Zollinger-Ellison Syndrome?

Stress does not cause Zollinger-Ellison Syndrome, but it can exacerbate symptoms, so stress management is important for those with the condition.

Are there support groups for people with Zollinger-Ellison Syndrome?

Yes, there are support groups and online communities where individuals and families can find information, resources, and support.

Can pregnancy affect Zollinger-Ellison Syndrome?

Pregnancy may worsen symptoms due to increased hormone levels, so it's important for women with the condition to work closely with healthcare providers during pregnancy.

Can alcohol consumption worsen Zollinger-Ellison Syndrome symptoms?

Alcohol can stimulate the release of stomach acid and may worsen symptoms, so it's best to limit or avoid alcohol consumption.

What should I discuss with my doctor if I suspect Zollinger-Ellison Syndrome?

It's important to discuss all symptoms, any family history of the condition, and any medications or supplements being taken with your doctor for an accurate diagnosis.

Can Zollinger-Ellison Syndrome affect children?

While rare, Zollinger-Ellison Syndrome can occur in children and may present with similar symptoms as in adults.

How can I manage the cost of Zollinger-Ellison Syndrome medication?

You can inquire with our pharmacy about potential savings programs, generic options, and other cost-saving measures for Zollinger-Ellison Syndrome medication.

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Information provided by Maryam Abdullahi-Mahdi. Reviewed by Mr. Matthew Liew