Lupus nephritis is a kidney disorder that occurs due to lupus, an autoimmune disease. It manifests as inflammation of the small blood vessels in the kidney and may lead to kidney failure. Symptoms include blood in the urine, high blood pressure, and swelling in the legs, ankles, or around the eyes.

Lupus Nephritis FAQ


What is lupus nephritis?

Lupus nephritis is a kidney disorder caused by systemic lupus erythematosus, an autoimmune disease.

What are the symptoms of lupus nephritis?

Symptoms include blood in the urine, foamy urine, high blood pressure, swelling in the legs and around the eyes, and protein in the urine.

How is lupus nephritis diagnosed?

Diagnosis involves blood and urine tests, imaging studies, and a kidney biopsy to confirm the condition and determine the extent of kidney damage.

What treatment options are available for lupus nephritis?

Treatment may include immunosuppressive medications, corticosteroids, antimalarial drugs, angiotensin-converting enzyme (ACE) inhibitors, and angiotensin receptor blockers (ARBs).

Can lupus nephritis be cured?

While there is no cure, early diagnosis and appropriate treatment can help manage the condition and prevent kidney damage.

Is lupus nephritis a life-threatening condition?

In severe cases, lupus nephritis can lead to kidney failure, which can be life-threatening. However, with proper management, the prognosis can be improved.

Are there lifestyle changes that can help manage lupus nephritis?

Maintaining a healthy diet, exercising regularly, avoiding smoking, managing stress, and getting enough rest can help manage lupus nephritis.

Is lupus nephritis more common in women?

Yes, lupus nephritis is more common in women of childbearing age, although it can affect individuals of any age or gender.

Can pregnancy affect lupus nephritis?

Pregnancy can pose risks for women with lupus nephritis, and it is important to discuss pregnancy planning and management with a healthcare professional.

What are the potential complications of untreated lupus nephritis?

Untreated lupus nephritis can lead to chronic kidney disease, kidney failure, cardiovascular disease, and other serious complications.

Can lupus nephritis cause permanent kidney damage?

Yes, if not properly managed, lupus nephritis can cause irreversible kidney damage. Early intervention is crucial to prevent long-term complications.

Is there a genetic predisposition to lupus nephritis?

Genetic factors may contribute to an individual's susceptibility to lupus nephritis, but the exact cause is not fully understood.

What are the long-term effects of lupus nephritis?

Long-term effects may include kidney damage, increased risk of cardiovascular disease, and potential impacts on overall health and quality of life.

How can I support a loved one with lupus nephritis?

Offer emotional support, assist with treatment adherence, engage in open communication, and help them maintain a healthy lifestyle.

Can lupus nephritis affect children?

Yes, while less common, children and adolescents can also develop lupus nephritis. Careful monitoring and treatment are essential in pediatric cases.

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Information provided by Maryam Abdullahi-Mahdi. Reviewed by Mr. Matthew Liew