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Actos Medication Information Leaflet

Common Use

Actos is commonly used to treat type 2 diabetes in adults by helping to control blood sugar levels.

Classification

Actos is classified as a thiazolidinedione (TZD) that improves the body's sensitivity to insulin.

Generic Ingredient

The generic compound for Actos is pioglitazone. It is available in the UK under both the brand name and various generic versions.

Certification Information

Actos is approved for use in several countries, including the UK, under specific regulatory certifications.

Known Alternatives in UK

Some known alternatives to Actos in the UK include metformin, sulphonylureas, and DPP-4 inhibitors.

Clinical Use

Actos is used in clinical practice as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Spectrum Of Activity

Actos primarily works by increasing insulin sensitivity, which helps the body to effectively utilize blood sugar.

Drug interaction

Actos may interact with other medications such as rifampicin, gemfibrozil, and certain oral contraceptives. It is important to consult a healthcare professional before starting or stopping any medications while taking Actos.

Dosage and Directions

The typical starting dose of Actos is 15 or 30 mg once daily, with or without food. Dosage may be adjusted by a healthcare professional based on individual response. It should be taken exactly as prescribed.

Contraindications and Precautions

Actos is contraindicated in patients with heart failure and should be used with caution in patients at risk for bladder cancer. It should not be used in individuals with a history of hypersensitivity to pioglitazone or any of its components.

Possible side effect

Common side effects of Actos include weight gain, edema, and upper respiratory tract infection. Other less common but serious side effects may occur, and it is important to seek medical advice if any unusual symptoms are experienced.

Missed dose and Overdose

If a dose is missed, it should be taken as soon as remembered unless it is almost time for the next dose. In case of overdose, medical attention should be sought immediately.

Storage

Actos should be stored at room temperature, away from moisture, heat, and light. It should be kept out of reach of children and pets.

Known Non-standard Use

In some cases, Actos may be used off-label for conditions not specified in the approved medication information. This should only be done under the guidance of a healthcare professional.

Special Cases

Special care should be taken when using Actos in elderly patients or those with hepatic impairment. Close monitoring and appropriate dose adjustments may be necessary.

Patient Considerations

Patients should be advised to continue following a healthy diet and exercise regimen while taking Actos. Regular monitoring of blood sugar levels and regular check-ups are also important.

Breastfeeding and Pregnancy

Actos is not recommended during pregnancy or breastfeeding, and an alternative treatment should be considered in these cases.

Possible Risks

There are risks associated with the use of Actos, such as an increased risk of bladder cancer and heart failure. These should be carefully considered and discussed with a healthcare professional before starting treatment.

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Actos FAQ

What is Actos used for?

Actos is used to treat type 2 diabetes by improving the body's response to insulin.

How should Actos be taken?

Actos should be taken as directed by a healthcare professional, usually once daily with or without food.

What are the common side effects of Actos?

Common side effects of Actos include weight gain, edema, and upper respiratory tract infection.

Can Actos be used in combination with other diabetes medications?

Actos can be used in combination with other diabetes medications, but the combination should be determined by a doctor.

Is Actos safe for long-term use?

Actos can be used for long-term treatment, but regular monitoring for potential side effects is essential.

What should I do if I miss a dose of Actos?

If a dose of Actos is missed, it should be taken as soon as remembered, unless it is almost time for the next dose.

Does Actos cause hypoglycemia?

Actos as a monotherapy is not known to cause hypoglycemia, but when used with insulin or other diabetes medications, it can increase the risk.

What are the warnings and precautions for Actos?

Actos may cause or worsen heart failure and its use is not recommended in patients with symptomatic heart failure.

Is Actos safe for use in pregnancy and breastfeeding?

Actos should not be used during pregnancy, and it is unknown if it passes into breast milk, so caution is advised.

Can Actos be used in children?

Actos is not recommended for use in children under 18 years of age.

How long does it take for Actos to start working?

Actos may start to lower blood sugar levels within a few days, but the full effects may take 2 to 3 months.

Does Actos cause cancer?

Actos has been associated with an increased risk of bladder cancer in some studies, so it should be used with caution in individuals with a history of bladder cancer.

Can Actos be taken with food?

Actos can be taken with or without food, as directed by a doctor.

Is Actos a form of insulin?

Actos is not a form of insulin; it works by increasing the body's sensitivity to insulin.