Buy Vigora
Vigora

1.6
Vigora (Sildenafil) is a medicinal treatment for erectile dysfunction in adult men. As a PDE5 inhibitor, it relaxes the muscles within the blood vessel walls, facilitating better circulation where needed. It is a widely used and trusted option for those looking to manage symptoms of impotence effectively.


Ingredient
Availability
In Stock
Delivery Time
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Sildenafil
Reference Brand
Viagra
Manufacturer
Zydus Cadila
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Men's Health
Product Category
Urologicals, Drugs used in Erectile Dysfunction
Pharmacological Class
PDE5 Inhibitor
Clinical Indications
Manufacturer Description
A medication widely used to treat impotence in men by enhancing the natural response to sexual arousal.
Mechanism of Action
It facilitates the relaxation of smooth muscles in the penis, which allows for increased blood flow when sexual arousal occurs, helping to sustain an erection.
Route of Administration
Oral
Onset Time
30-60 minutes
Duration
4 hours
Contraindications
Severe heart disease, Low blood pressure, Concurrent nitrate therapy
Severe Adverse Events
Sudden loss of vision, Hearing impairment, Chest pain, Fainting
Common Side Effects
Headache, Indigestion, Hot flushes
Uncommon Side Effects
Dizziness, Back pain, Stuffy nose
Drug Interactions
Isosorbide mononitrate, Erythromycin, Cimetidine, Grapefruit juice
Age Restrictions
Adults over 18.
Storage Guidelines
Store below 30°C in a dry place.
Related Products
Tadalafil, Sildenafil Generic

Vigora FAQ

Can Vigora be used more than once a day?

Vigora is approved for a maximum of one 100 mg dose within any 24-hour period. Taking more than this amount increases the risk of serious side effects without providing additional benefit.

Will Vigora affect my blood pressure?

Sildenafil can cause a modest reduction in blood pressure, especially when combined with nitrates or certain antihypertensive drugs. Most healthy men experience negligible changes, but individuals with cardiovascular disease should have their blood pressure monitored.

Is it safe to take Vigora with alcohol?

Moderate alcohol consumption does not typically interfere with the efficacy of Vigora, but excessive drinking can worsen dizziness or hypotension. It is advisable to limit intake to avoid potential side effects.

What should I do if I experience a prolonged erection?

A erection lasting longer than four hours (priapism) is a medical emergency. Seek immediate care at an emergency department; timely treatment reduces the risk of permanent penile damage.

Can I take Vigora if I am on an alpha-blocker for prostate enlargement?

Concurrent use can cause additive blood-pressure-lowering effects. If your prescriber recommends it, start with the lowest possible dose of Vigora and monitor for dizziness or faintness.

Does Vigora work for women?

Sildenafil is not approved for treating sexual dysfunction in women, and its safety and efficacy have not been established in this population.

How long before sexual activity should I take Vigora?

The medication should be taken approximately 30 minutes to 1 hour before anticipated sexual activity. Taking it earlier may delay onset, while taking it later may reduce effectiveness.

Will taking Vigora on an empty stomach make it work faster?

Yes, an empty stomach can lead to a quicker onset because food, especially high-fat meals, can delay absorption. However, the overall effectiveness remains comparable.

Is there a generic version of Vigora available in the UK?

Sildenafil is available as a generic prescription medicine in the UK. Generic formulations contain the same active ingredient and are subject to the same regulatory standards as Vigora.

What is Vigora?

Vigora is a brand-name medication that contains the active ingredient sildenafil. It is formulated as a 100 mg oral pill and belongs to the therapeutic class of erectile dysfunction (ED) treatments. In the United Kingdom, Vigora is classified as a prescription-only medicine (POM) and is regulated by the Medicines and Healthcare products Regulatory Agency (MHRA). The medication works by enhancing blood flow to the penis, helping men achieve and maintain an erection sufficient for sexual activity.

How Vigora Works in the Body

Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor. By blocking the PDE5 enzyme, it prevents the breakdown of cyclic guanosine monophosphate (cGMP) within the smooth muscle cells of the penile arteries. Elevated cGMP levels lead to relaxation of these smooth muscles, allowing the blood vessels to dilate and increase blood flow to the corpus cavernosum during sexual stimulation. The drug’s onset of action typically begins within 30-60 minutes, with peak effects occurring around 1 hour after ingestion. Its duration of effect can last up to 4-6 hours, depending on individual metabolism and dosage.

Conditions Treated by Vigora

Vigora is indicated for the treatment of erectile dysfunction in adult men. Erectile dysfunction is defined as the persistent inability to achieve or sustain an erection adequate for satisfactory sexual performance. The medication is intended for use only when sexual stimulation is present; it does not cause an erection without this stimulus.

Evidence-Based Off-Label Uses

Sildenafil, the active component of Vigora, has a well-documented approved indication for pulmonary arterial hypertension (PAH) under the brand name Revatio. While this is not an off-label use of Vigora, it demonstrates the broader therapeutic potential of the molecule.

Some clinical investigations have explored the use of sildenafil for:

  • Raynaud’s phenomenon - limited open-label studies suggest possible vasodilatory benefits, but robust randomized controlled trials are lacking.
  • High-altitude sickness - small pilot studies indicate reduced severity of altitude-related hypoxia, yet the evidence remains preliminary.

These applications are not approved by the MHRA for the Vigora brand. Any off-label use must be guided by a qualified healthcare professional, with careful risk-benefit assessment.

Who Should (Not) Use Vigora?

Ideal Candidates

  • Adult men diagnosed with erectile dysfunction who have adequate cardiovascular health to engage in sexual activity.
  • Individuals who have not responded satisfactorily to lifestyle modifications alone.

Absolute Contraindications

  • Known hypersensitivity to sildenafil or any of the pill’s excipients.
  • Simultaneous use of nitric oxide donors (e.g., nitroglycerin, isosorbide dinitrate) due to the risk of severe hypotension.
  • History of non-arteritic anterior ischemic optic neuropathy (NAION).

Relative Contraindications

  • Unstable angina or recent myocardial infarction (within the past 6 weeks).
  • Severe hepatic impairment (Child-Pugh class C).
  • Severe renal impairment (creatinine clearance < 30 mL/min).
  • Concurrent use of potent CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) which may increase sildenafil plasma levels.

Special Populations

  • Pregnancy and breastfeeding - not applicable, as the medication is intended for men.
  • Elderly - dose may need adjustment based on renal function and concomitant medications.
  • Patients using alpha-blockers - combined therapy can lead to additive blood-pressure-lowering effects; start at the lowest sildenafil dose and monitor closely.

If any of these conditions apply, discussion with a healthcare professional is essential before initiating therapy.

Safety Profile and Interactions

Common Side Effects

  • Headache - usually mild and transient.
  • Facial flushing - warmth and redness, often subsides without intervention.
  • Indigestion - may occur if the pill is taken on an empty stomach.
  • Nasal congestion - occasional stuffy nose.

Serious Adverse Events

  • Sudden loss of vision (possible NAION) - requires immediate medical evaluation.
  • Sudden hearing loss - also warrants urgent attention.
  • Priapism (prolonged erection lasting >4 hours) - a medical emergency; seek prompt care to prevent tissue damage.

Major Drug Interactions

  • Nitrates (e.g., glyceryl trinitrate) - co-administration can cause life-threatening hypotension.
  • CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir) - may raise sildenafil concentrations, increasing risk of side effects.
  • CYP3A4 inducers (rifampicin, carbamazepine) - can lower sildenafil levels, reducing efficacy.

Moderate Interactions

  • Alpha-blockers (tamsulosin, doxazosin) - monitor blood pressure; dose may need adjustment.
  • Antihypertensives - additive blood-pressure-lowering effect is possible but usually not severe.

Food and Lifestyle Interactions

  • High-fat meals can delay onset of action by 30-60 minutes; advisable to take the pill on an empty stomach for fastest effect.
  • Alcohol - excessive intake may exacerbate hypotension and dizziness; moderate consumption is generally acceptable.
  • Driving and machinery - most men do not experience impairment, but those who feel dizzy or light-headed should avoid operating vehicles until symptoms resolve.

Patients should disclose all prescription medicines, over-the-counter products, supplements, and herbal remedies to their prescriber to avoid unforeseen interactions.

How to Take Vigora

  • Standard dosing: One 100 mg tablet taken as needed approximately 30 minutes to 1 hour before anticipated sexual activity.
  • Maximum frequency: Do not exceed one tablet per 24 hours.
  • Adjustment for special populations:
  • Elderly or patients with moderate renal/hepatic impairment: The 100 mg dose is often appropriate, but clinicians may start at a lower dose (e.g., 50 mg) to assess tolerance.
  • Concomitant CYP3A4 inhibitors: Consider reducing to 50 mg to mitigate increased exposure.

Administration Tips

  • Swallow the pill whole with a glass of water; do not crush or chew.
  • The medication can be taken with or without food, but a high-fat meal may delay onset.
  • If a dose is missed because sexual activity is not planned, simply skip the dose - do not take an extra tablet later.

Overdose Management

Signs of overdose may include severe hypotension, prolonged erection, or intense headache. Immediate medical attention is recommended. No specific antidote exists; treatment is supportive, with attention to blood pressure and symptom relief.

Discontinuation

Vigora does not require tapering. If therapy is to be stopped, the medication can be discontinued abruptly without withdrawal symptoms.

Monitoring and Follow-Up

Routine laboratory monitoring is not required for most patients using sildenafil for erectile dysfunction. However, healthcare providers may:

  • Check blood pressure before initiating therapy, especially in patients with cardiovascular disease.
  • Assess cardiovascular status periodically if the patient has known heart conditions.
  • Review concomitant medications at each visit to detect potential interactions.

If side effects become severe or persistent, patients should contact their prescriber promptly.

Storage and Handling

  • Store Vigora at room temperature (15-30 °C), protected from excess moisture and light.
  • Keep the medication out of reach of children and pets.
  • Do not use the product after the expiry date printed on the packaging.
  • Dispose of unused tablets according to local pharmacy take-back schemes or the UK Medicines Act guidelines.

Medication-Specific Glossary

Phosphodiesterase type 5 (PDE5) inhibitor
A class of drugs that block the PDE5 enzyme, enhancing cGMP levels and promoting smooth-muscle relaxation in the penis.
cGMP (cyclic guanosine monophosphate)
A messenger molecule that mediates vasodilation; increased levels lead to improved blood flow.
Bioavailability
The proportion of the administered dose that reaches systemic circulation unchanged; sildenafil’s oral bioavailability is approximately 40 % due to first-pass metabolism.
Half-life
The time required for the plasma concentration of a drug to decrease by half; sildenafil’s half-life is about 4 hours.

Medical Disclaimer

This article provides educational information about Vigora and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Information for Vigora is sourced from established medical standards and updated frequently. It is provided for general guidance and should be confirmed with a healthcare professional before use.
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