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Travatan

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Travatan (Travoprost) is an ophthalmic solution used to treat high pressure inside the eye, including conditions like open-angle glaucoma. By increasing the natural drainage of fluid from the eye, it helps lower ocular pressure and protects the patient's vision from long-term damage.


Ingredient
Category
Availability
In Stock
Delivery Time
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Travoprost
Reference Brand
Travatan
Manufacturer
Novartis
Product Form
Eye drops
Regulatory Classification
Rx
Primary Category
Glaucoma Treatment, Eye Care
Product Category
Antiglaucoma preparations, Prostaglandin analogues
Pharmacological Class
Prostaglandin F2-alpha analogue
Manufacturer Description
An effective eye drop for managing pressure in the eye associated with glaucoma.
Mechanism of Action
Travatan increases the natural outflow of fluid from within the eye into the bloodstream. By reducing the buildup of aqueous humour, it lowers the internal pressure of the eye, preventing damage to the optic nerve and preserving vision.
Route of Administration
Ophthalmic
Onset Time
2 hours
Duration
24 hours
Contraindications
Hypersensitivity to travoprost, Pregnancy, Breastfeeding
Severe Adverse Events
Changes in iris colour, Inflammation of the iris, Blurred vision
Common Side Effects
Mild eye redness, Itchy eyes, Dry eyes
Uncommon Side Effects
Darkening of eyelid skin, Increased eyelash growth, Eye discomfort
Drug Interactions
Other ophthalmic prostaglandins, Bimatoprost, Latanoprost
Pregnancy Safety Warnings
Not recommended during pregnancy or breastfeeding.
Age Restrictions
Not recommended for children under 18 years
Storage Guidelines
Store below 25°C. Discard 4 weeks after opening.
Related Products
Lumigan, Xalatan, Monopost

Travatan FAQ

Can Travatan be used for conditions other than glaucoma?

Travatan is specifically approved for primary open-angle glaucoma and ocular hypertension. Off-label use for other eye conditions has not been established with sufficient evidence, and any such use should be discussed with an eye-care specialist.

What should I do if I experience darkening of my iris?

Iris colour change is a known, usually permanent effect of prostaglandin analogues. If the change is concerning or accompanied by other symptoms, schedule an appointment with your ophthalmologist for evaluation.

Is it safe to use Travatan while wearing contact lenses?

Contact lenses should be removed before instilling Travatan. Wait at least 15 minutes after dosing before reinserting lenses to avoid drug adsorption onto the lens material.

Can I use other eye drops together with Travatan?

Certain eye drops, such as non-steroidal anti-inflammatory drops, may diminish Travatan’s effect. Always inform your eye-care provider about all ocular medications you are using.

How long does it take for Travatan to start lowering eye pressure?

Travatan begins to reduce intra-ocular pressure within a few hours after administration, with the maximum effect typically observed 8-12 hours later.

After opening, the bottle should be used within 30 days. Discard any remaining solution beyond this period, even if the expiration date on the label is later.

Are there any travel restrictions for carrying Travatan on an airplane?

Travatan can be carried in hand luggage in its original container. It is advisable to keep the bottle in a clear, resealable plastic bag and carry a copy of the prescription if requested by security personnel.

Does Travatan affect my ability to drive or operate machinery?

Travatan does not impair vision or cognitive function. However, if you experience transient blurred vision after dosing, wait until vision clears before driving.

Can Travatan cause systemic side effects?

Systemic absorption of travoprost from eye drops is minimal. Report any unexpected systemic symptoms, such as headaches or respiratory changes, to a healthcare professional.

What are the cost considerations for Travatan compared with generic travoprost?

Travatan is a brand-name formulation; generic travoprost eye drops may be available at a lower price. Pricing can vary by pharmacy and region, and patients should discuss options with their prescriber and pharmacist.

What is Travatan?

Travatan is a prescription eye-drop medication that contains the active ingredient travoprost. It belongs to the class of prostaglandin-F2α analogues, a group of drugs used to lower intra-ocular pressure (IOP) in conditions such as primary open-angle glaucoma and ocular hypertension. Travatan is supplied in a sterile 2.5 ml bottle of ophthalmic solution and is regulated in the United Kingdom by the Medicines and Healthcare products Regulatory Agency (MHRA).

How Travatan Works in the Body

Travoprost is a synthetic analogue of prostaglandin F2α. After the drop is placed on the eye’s surface, the drug is absorbed through the cornea and binds to prostanoid FP receptors in the ciliary muscle. This binding triggers a cascade that increases the outflow of aqueous humor via the uveoscleral pathway, thereby reducing intra-ocular pressure. The medication begins to lower IOP within a few hours, reaches its peak effect after 8-12 hours, and the pressure-lowering effect can last for about 24 hours, allowing once-daily dosing.

Conditions Treated with Travatan

Travatan is approved by the MHRA for the following indications:

  • Primary open-angle glaucoma (POAG)
  • Ocular hypertension (OHT)

These conditions are characterized by elevated intra-ocular pressure that can damage the optic nerve and lead to progressive vision loss if untreated. Travatan is intended for adult patients who require a topical therapy to lower IOP and preserve visual function.

Patient Suitability and Contra-indications

Who Should Use Travatan?

  • Adults diagnosed with POAG or OHT who need IOP reduction.
  • Patients who can administer eye drops reliably and adhere to once-daily evening dosing.

Absolute Contra-indications

  • Known hypersensitivity to travoprost, any component of the formulation, or other prostaglandin analogues.
  • Active ocular infections (e.g., bacterial, viral, fungal) in the eye to be treated.

Relative Contra-indications and Special Populations

  • Pregnancy and breastfeeding: Travoprost is classified as Category C in the UK; it should only be used if the potential benefit justifies the potential risk to the fetus or infant.
  • Pediatric use: Safety and efficacy have not been established in children; use is generally limited to adults.
  • Elderly patients: No dose adjustment is required solely because of age, but clinicians may monitor IOP response and ocular surface tolerance more closely.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Eye redness (hyperemia): frequently reported, usually mild and transient.
  • Eye irritation or foreign-body sensation: often resolves within a few days.
  • Increased eyelash growth (hypertrichosis): may be cosmetically noticeable.
  • Iris colour change: brown or darkening of the iris can occur with long-term use.

Serious Adverse Events

  • Anterior uveitis or iritis: inflammation of the eye’s middle layer; requires immediate ophthalmologic evaluation.
  • Severe ocular pain or vision loss: rare; treat as an emergency.

Drug Interactions

Travoprost has a low potential for systemic drug interactions because it is administered locally. However:

  • Non-steroidal anti-inflammatory eye drops (e.g., ketorolac): may reduce the IOP-lowering effect of travoprost.
  • Other prostaglandin analogues or IOP-lowering agents: concurrent use may increase the risk of ocular side effects; combination therapy should be managed by an eye-care professional.

Food and Lifestyle Interactions

  • No known food interactions.
  • Alcohol does not affect the efficacy of travoprost, but excessive drinking may impair the ability to apply eye drops safely.
  • Patients should avoid rubbing their eyes after instillation to prevent drug loss and contamination.

How to Take Travatan

  • Standard dosing: Instil one drop (approximately 0.05 ml) in the affected eye(s) once daily in the evening.
  • Administration tips:
  • Wash hands before use.
  • Tilt the head back, pull down the lower eyelid to create a small pocket, and place the drop without touching the bottle tip to the eye or eyelashes.
  • Close the eye gently for 1-2 minutes; apply light pressure to the inner corner of the eye to reduce systemic absorption.
  • Missed dose: If a dose is missed, apply it as soon as remembered unless it is near the time of the next scheduled dose. Do not double the dose.
  • Overdose: Accidental administration of more than one drop is unlikely to cause serious systemic toxicity, but patients should contact a healthcare professional if they experience significant eye irritation, blurred vision, or systemic symptoms.
  • Discontinuation: Travoprost can be stopped abruptly; however, IOP may rise. Patients should discuss any changes in therapy with their eye-care provider.

Monitoring and Follow-Up

  • IOP measurement: Baseline IOP should be recorded before initiating therapy, followed by checks at 4-6 weeks and then periodically (e.g., every 3-6 months) to ensure adequate pressure control.
  • Ocular examination: Regular slit-lamp examinations are recommended to monitor for ocular surface changes, iris pigmentation, and signs of inflammation.
  • Adverse-event reporting: Any new or worsening eye symptoms should be reported promptly to an ophthalmologist.

Storage and Handling

  • Store the Travatan bottle at room temperature (15-30 °C), away from direct sunlight and moisture.
  • Do not freeze the solution.
  • Keep the bottle tightly closed when not in use and out of reach of children.
  • Discard any remaining solution after 30 days of opening, even if the expiration date has not been reached, to maintain sterility.

Medication-Specific Glossary

Prostaglandin analogue
A synthetic compound that mimics the activity of natural prostaglandins, used in ophthalmology to increase aqueous-humor outflow.
Intra-ocular pressure (IOP)
The fluid pressure inside the eye; elevated IOP is a major risk factor for glaucoma.
Uveoscleral outflow
One of the pathways by which aqueous humor exits the eye, targeted by prostaglandin analogues to lower IOP.
Hyperemia
Redness of the eye caused by dilation of conjunctival blood vessels.
Hypertrichosis
Excessive hair growth, in this context referring to increased eyelash length and density.

Medical Disclaimer

This article provides educational information about Travatan and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Information for Travatan is sourced from established medical standards and updated frequently. It is provided for general guidance and should be confirmed with a healthcare professional before use.
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