Buy Stromectol
Stromectol

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Stromectol (ivermectin) is a broad-spectrum antiparasitic agent used to treat specific parasitic infections. It works by interfering with the nervous system and muscle function of parasites, ultimately neutralising them. This medication is essential for managing various internal and external parasitic conditions in adult patients.


Ingredient
Availability
In Stock
Delivery Time
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Ivermectin
Reference Brand
Ivermectin
Manufacturer
Merck Sharp & Dohme
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Parasitic Infection Treatment
Product Category
Antiparasitic products, Anthelmintics
Pharmacological Class
Avermectins
Manufacturer Description
An antiparasitic medication used to treat certain infestations of worms and mites like scabies.
Mechanism of Action
It works by binding to nerve and muscle cells of the parasite, increasing their permeability to chloride ions. This causes paralysis and eventual death of the parasite. In humans, it generally does not cross the blood-brain barrier which protects from these effects.
Route of Administration
Oral
Onset Time
Starts working immediately (parasite death)
Duration
Remains active in the body for several days
Contraindications
Hypersensitivity to ivermectin, Severe asthma
Severe Adverse Events
Vision changes, Severe skin rash, Inability to control urination or bowel movements, Confusion
Common Side Effects
Dizziness, Appetite loss, Nausea
Uncommon Side Effects
Muscle pain, Joint pain, Swollen lymph nodes
Drug Interactions
Warfarin, Valproic acid
Pregnancy Safety Warnings
Avoid during pregnancy unless directed by specialist.
Age Restrictions
Not recommended for children weighing less than 15kg
Storage Guidelines
Store below 30°C in a dry place.
Related Products
Permethrin (topical), Malathion

Stromectol FAQ

Can I travel internationally with Stromectol tablets?

Yes, you may travel with a prescription supply of Stromectol, but it is advisable to carry the original pharmacy label and a copy of your prescription. Some countries may require proof of prescription at the border, so keeping documentation handy can prevent delays.

Will taking Stromectol affect drug-testing results for work or sport?

Ivermectin is not listed as a prohibited substance by the World Anti-Doping Agency (WADA) for athletes, nor is it commonly screened for in standard occupational drug tests. However, disclose any medication use to your employer or sports governing body if required.

What does a Stromectol tablet look like?

In the UK, the 3 mg tablet is white and round, the 6 mg tablet is white and oval, and the 12 mg tablet is white, round, and bears the imprint “IVM 12 MSD”. Appearance may vary slightly by batch, but dosage markings are consistent.

Is Stromectol the same as generic ivermectin?

Stromectol is a branded formulation of the active ingredient ivermectin. The generic version contains the same compound in identical strengths and is therapeutically equivalent, though inactive ingredients (excipients) may differ.

Can children under five years old take Stromectol for scabies?

Ivermectin is generally not recommended for children weighing less than 15 kg or younger than five years, except in severe scabies where the benefits may outweigh the risks. Pediatric dosing should be determined by a pediatrician.

Do I need to avoid certain foods while on Stromectol?

Ivermectin absorption can increase slightly when taken with a high-fat meal, but this effect is not clinically significant. You may take the tablet with or without food; choose the option that minimizes gastrointestinal discomfort.

How long does a Stromectol tablet remain effective after its expiration date?

Do not use tablets past the printed expiry date. Chemical stability cannot be guaranteed beyond this point, and efficacy may be reduced. If you possess expired medication, discard it safely according to NHS guidelines.

Are there any cost differences between Stromectol and generic ivermectin in the UK?

Brand-name Stromectol may be priced higher than generic ivermectin due to branding and packaging. NHS prescription charges apply uniformly, but private purchases can vary. Discuss pricing options with your pharmacist.

What regulatory bodies oversee Stromectol in the UK?

Stromectol is licensed by the Medicines and Healthcare products Regulatory Agency (MHRA). Clinical guidelines for its use are provided by NICE and the British Society for Antimicrobial Chemotherapy (BSAC).

Has Stromectol been proven effective for COVID-19?

Current high-quality clinical evidence does not support the use of ivermectin for preventing or treating COVID-19. Major health agencies, including the MHRA and WHO, advise against its routine use for this purpose outside of a controlled trial.

What is Stromectol?

Stromectol is a prescription-only medication marketed in the United Kingdom under the brand name Stromectol. Its single active ingredient is ivermectin, an antiparasitic agent that belongs to the macrocyclic lactone class. Stromectol is supplied as oral tablets (pill form) in three strengths: 3 mg, 6 mg, and 12 mg. The product is manufactured by Merck Sharp & Dohme (MSD) and is regulated by the Medicines and Healthcare products Regulatory Agency (MHRA). While ivermectin is approved for several parasitic infections, its use for COVID-19 remains investigational and is not endorsed by UK authorities.

How Stromectol Works in the Body

Ivermectin exerts its antiparasitic effect by binding selectively to glutamate-gated chloride channels found in the nerve and muscle cells of many invertebrates. This binding increases the flow of chloride ions into the cells, causing hyperpolarisation, paralysis, and ultimately death of the parasite. Human cells lack these specific channels, which accounts for the drug’s relatively high safety margin when used at approved doses.

For the few viruses that have been studied in the laboratory, ivermectin appears to inhibit replication by interfering with the import of viral proteins into the host cell nucleus (a process mediated by the importin α/β pathway). These antiviral mechanisms have been demonstrated only in cell-culture experiments; clinical relevance in humans, including for SARS-CoV-2, has not been established.

Conditions Treated with Stromectol

Stromectol is authorised in the UK for the following indications:

  • Strongyloidiasis (infection with Strongyloides stercoralis)
  • Onchocerciasis (river blindness caused by Onchocerca volvulus)
  • Scabies (caused by Sarcoptes scabiei)
  • Lice infestations (head and body lice)

The choice of dose and treatment duration depends on the specific infection, the patient’s weight, and any comorbid conditions. Ivermectin is not approved for the prevention or treatment of COVID-19 by the MHRA, the National Institute for Health and Care Excellence (NICE), or any other UK regulatory body.

Evidence-Based Off-Label Uses

Investigational Use for COVID-19

During the COVID-19 pandemic, ivermectin was evaluated in several laboratory studies and clinical trials as a potential antiviral agent. To date:

  • Large, well-designed randomised controlled trials have not demonstrated a consistent, clinically meaningful benefit of ivermectin in preventing infection, reducing hospitalisation, or improving survival.
  • Regulatory agencies, including the MHRA and the World Health Organization (WHO), have issued statements that current evidence does not support routine use of ivermectin for COVID-19 outside of a clinical trial setting.

Off-label disclaimer: Use of Stromectol for COVID-19 is considered off-label and should only occur within the context of a supervised clinical trial or after a detailed risk-benefit discussion with a qualified healthcare professional.

Who Should (and Should Not) Use Stromectol?

Absolute Contraindications

  • Known hypersensitivity to ivermectin or any component of the tablet.
  • Documented infection with Loa loa (African eye worm). In individuals with high Loa loa microfilaraemia, ivermectin can precipitate severe, potentially fatal encephalopathy.

Relative Contraindications & Cautions

  • Pregnancy - Ivermectin is classified as Category C in the UK; animal studies have shown adverse fetal effects, and human data are limited. Use only if the potential benefit outweighs the risk.
  • Breastfeeding - Small amounts are excreted in breast milk; caution is advised, especially for infants under two months.
  • Severe hepatic impairment - Reduced drug clearance may increase exposure; dose adjustment or alternative therapy should be considered.
  • Renal disease - No dose adjustment is required for mild to moderate renal impairment, but severe renal failure warrants clinical judgment.

Special Populations

  • Children - Ivermectin is generally not recommended for children weighing less than 15 kg or younger than five years, except for scabies where the benefit may outweigh the risk.
  • Elderly - No specific dosing change is required, but age-related organ dysfunction should be assessed.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Dizziness or light-headedness - usually mild and transient.
  • Pruritus or rash - often a reaction to dying parasites rather than the drug itself.
  • Gastrointestinal upset - nausea, diarrhoea, or abdominal pain in up to 10 % of patients.
  • Fatigue - reported in a minority of individuals.

Serious Adverse Events

  • Neurological complications - seizures, confusion, or ataxia are rare but possible, especially in patients with Loa loa infection.
  • Severe cutaneous reactions - Stevens-Johnson syndrome or toxic epidermal necrolysis have been reported sporadically.
  • Hepatotoxicity - isolated case reports exist; monitor liver function if prolonged therapy is required.

Drug Interactions

Interaction Level Example Drugs Clinical Note
Major Warfarin - theoretical increase in anticoagulant effect; monitor INR.
Moderate Cytochrome P450 3A4 inhibitors (e.g., ketoconazole, clarithromycin) - may raise ivermectin levels; consider dose adjustment.
Minor Other antiparasitics - additive central nervous system effects; avoid unnecessary combination.

Patients should disclose all prescription medicines, over-the-counter products, herbal supplements, and vitamins before starting Stromectol.

Food and Lifestyle Interactions

  • Meals - A fatty meal modestly increases ivermectin absorption; the tablet may be taken with or without food according to patient preference.
  • Alcohol - No direct interaction, but excessive alcohol may exacerbate dizziness.
  • Operating machinery - Use caution until you know how the medication affects you, especially if you experience dizziness.
  • Sun exposure - No specific photosensitivity reported, but general skin protection is advisable.

How to Take Stromectol

Standard Dosing (based on available tablet strengths)

| Indication | Typical Adult Dose* | Tablet Strength Used | |||-| | Strongyloidiasis | 200 µg/kg as a single dose (≈12 mg for a 60 kg adult) | 12 mg tablet | | Onchocerciasis | 150 µg/kg once, repeated after 6-12 months | 6 mg or 12 mg tablets | | Scabies (adults) | 200 µg/kg on day 1 and repeated after 7 days | 12 mg tablet | | Lice | 200 µg/kg single dose | 12 mg tablet |

*Doses are weight-based; tablets can be split under pharmacy guidance to achieve the appropriate amount.

Special Population Adjustments

  • Pregnant or breastfeeding women: Use only if the expected benefit justifies potential risk; dosing remains weight-based.
  • Severe hepatic impairment: Consider 50 % dose reduction; close monitoring is required.
  • Children ≥15 kg: Apply the same weight-based calculations; tablets may need to be divided.

Administration Tips

  • Swallow tablets whole with a full glass of water.
  • The pill may be taken with food to improve tolerability.
  • Store tablets in the original container, tightly closed, at room temperature (15-30 °C), protected from moisture and light.

Missed Dose

If you forget a dose and are within 12 hours of the scheduled time, take it as soon as you remember. If it is later than 12 hours, skip the missed dose and resume your regular schedule. Do not double-dose without professional advice.

Overdose Management

Signs of ivermectin overdose may include severe dizziness, tremor, ataxia, or seizures. In the event of suspected overdose:

  • Seek emergency medical care immediately.
  • Provide the exact amount taken and the time of ingestion.
  • No specific antidote exists; treatment is supportive, focusing on airway protection, seizure control, and monitoring of vital signs.

Discontinuation

Therapy is usually short-term; abrupt cessation is not an issue. If a severe adverse reaction occurs, discontinue the medication and contact a healthcare professional promptly.

Monitoring and Follow-Up

  • Clinical response - Assess resolution of parasitic symptoms (e.g., pruritus, skin lesions) within 1-2 weeks of treatment.
  • Laboratory tests - Baseline liver function tests are advisable for patients with known hepatic disease; repeat if clinically indicated.
  • Adverse event surveillance - Educate patients to report neurological symptoms, rash, or persistent gastrointestinal upset.

Routine laboratory monitoring is not required for uncomplicated infections in otherwise healthy adults.

Storage and Handling

  • Keep tablets in the original blister pack until use.
  • Store at 20-25 °C (room temperature); do not refrigerate or freeze.
  • Protect from excessive humidity and direct sunlight.
  • Keep out of reach of children; use a child-proof container if necessary.
  • Dispose of unused tablets according to local pharmacy take-back programs or follow the NHS “medicines waste” guidelines.

Medication-Specific Glossary

Glutamate-Gated Chloride Channel
A protein found in the nerve and muscle cells of many invertebrates; ivermectin binds to this channel, causing an influx of chloride ions that leads to paralysis of the parasite.
Macrocyclic Lactone
The chemical class to which ivermectin belongs; characterised by a large ring structure that confers potent antiparasitic activity.
Hyperinfection Syndrome
An overwhelming proliferation of Strongyloides larvae that can occur in immunocompromised individuals if the infection is not adequately treated.
Loa loa
A filarial worm endemic to West and Central Africa; high microfilaraemia can precipitate severe neurologic toxicity when treated with ivermectin.
Weight-Based Dosing (µg/kg)
A method of calculating drug dosage according to a patient’s body weight in micrograms per kilogram, ensuring appropriate drug exposure across diverse body sizes.

Medical Disclaimer

This article provides educational information about Stromectol and is not a substitute for professional medical advice. Treatment decisions, including the use of any medication for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes only and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Information for Stromectol is sourced from established medical standards and updated frequently. It is provided for general guidance and should be confirmed with a healthcare professional before use.
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