Buy Salbutamol
Salbutamol

16.37
Generic Salbutamol is a short-acting beta-2 agonist used as a bronchodilator to treat asthma and COPD. It provides rapid relief from chest tightness and shortness of breath by relaxing the muscles in the walls of the small airways in the lungs, making breathing significantly easier.


Ingredient
Availability
In Stock
Delivery Time
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Salbutamol
Reference Brand
Ventolin
Manufacturer
GSK
Product Form
Inhaler, Nebuliser solution, Tablets
Regulatory Classification
Rx
Primary Category
Asthma Relief, Respiratory Care
Product Category
Drugs for obstructive airway diseases, Selective beta-2-adrenoreceptor agonists
Pharmacological Class
Short-acting beta-agonist (SABA)
Manufacturer Description
A 'reliever' inhaler used to quickly open the airways during breathing difficulties.
Mechanism of Action
It quickly relaxes the muscles in the walls of the small airways in the lungs. This helps to open the airways and makes it easier to breathe during an asthma attack or when short of breath.
Route of Administration
Inhalation
Onset Time
5-15 minutes
Duration
3-6 hours
Contraindications
Hypersensitivity to salbutamol, Threatened abortion (oral form)
Severe Adverse Events
Bronchospasm (wheezing after use), Low potassium, Chest pain
Common Side Effects
Shaky hands, Nervousness, Headache
Uncommon Side Effects
Racing heartbeat, Muscle cramps, Palpitations
Drug Interactions
Beta-blockers, Diuretics
Pregnancy Safety Warnings
Safe to use during pregnancy if required.
Age Restrictions
Suitable for all ages as prescribed
Storage Guidelines
Store below 30°C. Protect from frost and direct sunlight.
Related Products
Salamol, Airomir, Terbutaline

Salbutamol FAQ

Can I use a Salbutamol inhaler before a marathon?

Yes, a common practice is to take 1-2 puffs (100 µg each) about 15 minutes before intense exercise to prevent bronchoconstriction. If you have never used salbutamol for this purpose, discuss the plan with a healthcare professional to confirm the appropriate timing and dosage.

What should I do if I experience a tremor after inhaling Salbutamol?

Mild tremor is a typical side effect and usually resolves on its own. If it is severe, persists, or interferes with daily activities, contact your prescriber; they may adjust the dose or consider an alternative therapy.

Is Salbutamol safe to use while breastfeeding?

Salbutamol does pass into breast milk in small amounts and is generally considered compatible with breastfeeding (UK Category B). The benefits of treating maternal asthma usually outweigh potential risks to the infant, but discuss any concerns with your doctor.

How long can I rely solely on a Salbutamol inhaler for asthma control?

Salbutamol provides rapid relief but does not treat underlying inflammation. If you need your rescue inhaler more than twice a week, a controller medication (e.g., inhaled corticosteroid) may be required. Regular review with a clinician is essential.

Can I store my Salbutamol inhaler in a car during summer?

No. High temperatures can degrade the medication and impair performance. Keep the inhaler in a temperature-controlled environment; avoid exposure to direct sunlight or a hot vehicle interior.

What is the difference between Salbutamol and Formoterol?

Salbutamol is a short-acting β2-agonist delivering relief within minutes, lasting up to 6 hours. Formoterol is a long-acting β2-agonist (LABA) that provides bronchodilation for 12 hours and is used as a maintenance therapy, not for immediate rescue.

Do I need a spacer device with my Salbutamol inhaler?

A spacer can improve drug delivery, especially for children or individuals with coordination difficulties. Adults who can achieve a good inhalation technique may use the inhaler without a spacer, but a spacer is optional.

Will Salbutamol show up on a drug test for work or sport?

Salbutamol is not a prohibited substance in most sporting contexts, but athletes should check the specific regulations of their governing body. Routine workplace drug screens generally do not test for inhaled bronchodilators.

Is it possible to become dependent on Salbutamol?

Physical dependence is not typical, but over-reliance on rescue medication can indicate poorly controlled asthma. Frequent need for Salbutamol suggests the need for a review of long-term asthma management.

Can I switch from a 100 µg inhaler to a 200 µg inhaler without consulting a doctor?

No. Dosage strength should be prescribed by a healthcare professional. Switching devices or strengths without guidance may lead to under- or overdosing and increase the risk of side effects.

Salbutamol: Generic Medication Overview

Salbutamol is a short-acting β2-adrenergic agonist (SABA) used to relax the smooth muscles of the airways. In the United Kingdom it is supplied as an inhaler containing 100 µg of salbutamol per actuation. The inhaler is classified as a prescription-only medicine (POM) and is widely prescribed for the rapid relief of bronchospasm associated with asthma, chronic obstructive pulmonary disease (COPD), and exercise-induced bronchoconstriction. Various manufacturers market salbutamol inhalers under different brand names, but the active ingredient and therapeutic action are the same.

How Salbutamol Works in the Body

Salbutamol binds selectively to β2-adrenergic receptors on the smooth muscle lining the airways. Activation of these receptors stimulates the enzyme adenylate cyclase, increasing intracellular cyclic adenosine monophosphate (cAMP). Elevated cAMP leads to relaxation of bronchial smooth muscle, producing bronchodilation within minutes. The onset of relief is typically 5-15 minutes, the peak effect occurs around 30 minutes, and the duration of action lasts 4-6 hours. Because salbutamol is inhaled, a high proportion reaches the lungs directly, providing rapid local effect with minimal systemic exposure.

Conditions Treated by Salbutamol

  • Acute asthma attacks - rapid relief of wheeze, breathlessness, and chest tightness.
  • Chronic obstructive pulmonary disease (COPD) - relief of reversible bronchospasm.
  • Exercise-induced bronchoconstriction - prevention of airway narrowing that occurs during or after physical activity.

These indications are approved by the UK Medicines and Healthcare products Regulatory Agency (MHRA) and are reflected in NICE guideline NG80 for asthma management.

Who Should Not Use Salbutamol?

Absolute contraindications

  • Known hypersensitivity to salbutamol or any other ingredient of the inhaler.

Relative contraindications / cautions

  • Cardiovascular disease - tachyarrhythmias, angina, or severe hypertension may be worsened by β2-agonist effects.
  • Pregnancy and lactation - salbutamol is classed as Category B (UK). Use only if clearly needed; the benefits should outweigh potential risks.
  • Pediatric patients - dosing differs; the 100 µg inhaler is generally intended for adults and adolescents over 12 years.

Patients with these conditions should discuss the suitability of salbutamol with their healthcare professional before initiating therapy.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Tremor (particularly of the hands) - often transient.
  • Palpitations or mild tachycardia.
  • Throat irritation or cough after inhalation.
  • Headache.

These effects are usually mild and resolve without intervention. Rinsing the mouth with water after inhalation can reduce throat irritation.

Serious Adverse Events

  • Paradoxical bronchospasm - sudden worsening of breathlessness after use; requires immediate medical review.
  • Severe tachyarrhythmias - especially in patients with pre-existing heart disease.
  • Hypokalemia - low blood potassium levels may occur with excessive use; monitor if high-dose therapy is needed.

Any of these symptoms warrant urgent medical attention.

Drug Interactions

  • β-blockers (e.g., propranolol) - may diminish salbutamol’s bronchodilator effect and increase the risk of bronchospasm.
  • Diuretics (e.g., furosemide) - can potentiate hypokalemia when combined with frequent salbutamol use.
  • MAO inhibitors and tricyclic antidepressants - may enhance cardiovascular stimulation.

Patients should inform their prescriber of all current medicines, including over-the-counter drugs and herbal supplements.

Food and Lifestyle Interactions

  • Food - no significant food-drug interaction; salbutamol can be taken with or without meals.
  • Alcohol - modest amounts generally do not affect salbutamol, but excessive consumption may increase heart rate.
  • Driving or operating machinery - if you experience tremor or palpitations, exercise caution until you know how the medication affects you.

How to Take Salbutamol

  • Standard dosing for acute relief: 1-2 inhalations (100 µg each) as needed for bronchospasm. If symptoms persist, repeat after 20 minutes; do not exceed 4 puffs in one hour.
  • Maximum daily dose: Typically no more than 12 inhalations (1.2 mg) per day, unless a clinician advises otherwise.
  • Exercise-induced bronchoconstriction: Take 1-2 puffs 15 minutes before planned exercise.
  • Administration technique:
  • Remove the cap and shake the inhaler gently.
  • Exhale fully, place the mouthpiece between your lips, and seal tightly.
  • Press the canister once while beginning a slow, steady inhalation.
  • Hold your breath for about 10 seconds, then exhale slowly.
  • Missed dose: If you forget a dose and it is still within the usual dosing interval, take it as soon as you remember. Do not double the next scheduled dose.
  • Overdose: Symptoms may include rapid heart rate, severe tremor, nausea, or muscle cramps. Seek immediate medical help; treatment is supportive, with oxygen and, if needed, a short-acting anticholinergic (e.g., ipratropium) for bronchodilation.
  • Discontinuation: Salbutamol does not require tapering. If therapy is stopped, monitor for return of bronchospasm and contact a clinician if symptoms recur.

Monitoring and Follow-Up

  • Symptom diary - record frequency of inhaler use, nocturnal awakenings, and peak expiratory flow (PEF) readings.
  • Peak flow monitoring - helps assess control; a sustained increase in PEF after using salbutamol suggests good response.
  • Routine review - schedule a review with your GP or respiratory nurse at least annually, or sooner if you require more than the usual number of puffs per week.
  • Laboratory tests - not routinely required for salbutamol, but potassium levels may be checked in patients on high doses or concomitant diuretics.

Storage and Handling

  • Store the inhaler at room temperature (15-25 °C), away from direct heat and moisture.
  • Keep the device in a dry place; avoid leaving it in a bathroom cabinet where humidity is high.
  • Do not freeze the inhaler.
  • Replace the inhaler once the dose counter reaches zero or after the expiry date printed on the packaging.
  • Keep out of reach of children; the inhaler should be stored in a locked cabinet if support is needed.

Medication-Specific Glossary

β2-adrenergic receptor
A protein on airway smooth muscle that, when stimulated by agents like salbutamol, causes muscle relaxation and bronchodilation.
Bronchodilation
The widening of the airways, resulting in improved airflow and reduced breathing difficulty.
Peak Expiratory Flow (PEF)
The highest speed of exhalation measured with a peak flow meter; used to monitor asthma control and response to bronchodilators.

Medical Disclaimer

This article provides educational information about Salbutamol and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Information for Salbutamol is sourced from established medical standards and updated frequently. It is provided for general guidance and should be confirmed with a healthcare professional before use.
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