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Heximar Ointment

39.1
Heximar Ointment is a topical treatment used to manage plaque psoriasis. It typically contains ingredients that help slow the overproduction of skin cells and reduce inflammation. This provides relief from scaling, redness, and irritation, helping to restore the skin's natural appearance and comfort for adult patients.


Ingredient
Category
Availability
In Stock
Delivery Time
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Calcipotriol
Reference Brand
Dovonex
Manufacturer
Glenmark Pharmaceuticals
Product Form
Ointment, Cream
Regulatory Classification
Rx
Primary Category
Skin Care, Psoriasis Treatment
Product Category
Dermatologicals, Antipsoriatics
Pharmacological Class
Vitamin D analogue
Manufacturer Description
A topical treatment specifically designed to manage stable plaque psoriasis by regulating skin cell renewal.
Mechanism of Action
Calcipotriol is a derivative of Vitamin D that slows down the overproduction of skin cells. This helps to flatten and clear psoriasis plaques.
Route of Administration
Topical
Onset Time
1-2 weeks for visible effect
Duration
12 hours
Contraindications
Calcium metabolism disorders, Hypercalcaemia, Severe kidney or liver disease
Severe Adverse Events
Hypercalcaemia, Photosensitivity, Changes in skin pigmentation
Common Side Effects
Skin irritation, Itching, Burning sensation
Uncommon Side Effects
Dermatitis, Erythema, Dry skin
Drug Interactions
Salicylic acid topical, Systemic Vitamin D supplements
Pregnancy Safety Warnings
Use only if benefit outweighs risk
Age Restrictions
Consult doctor for children
Storage Guidelines
Store below 25°C; do not refrigerate
Related Products
Dovonex, Enstilar

Heximar Ointment FAQ

Can Heximar Ointment be used on the scalp?

Heximar Ointment is formulated for use on body skin and is not recommended for the scalp, where hair may impede proper coverage. Patients with scalp psoriasis should discuss alternative formulations, such as shampoos or solutions, with their clinician.

What should I do if I experience severe skin irritation?

If the treated area becomes intensely red, swollen, or blistered, stop using the ointment and seek medical attention promptly. The prescriber may suggest a temporary discontinuation or a switch to a different therapy.

Is it safe to apply Heximar Ointment before bedtime?

Applying the ointment at night is common practice because it allows the medication to remain undisturbed while the skin repairs. Ensure the area is clean and dry before application.

How long does a 15 g tube typically last?

A 15 g tube generally provides enough product for 2-3 weeks of once-daily application, depending on the size and number of lesions treated.

Can I use other topical creams alongside Heximar Ointment?

Concurrent use of other topical agents should be coordinated with a healthcare professional. Some creams may interfere with absorption or increase irritation risk.

Does Heximar Ointment require a prescription in the UK?

Yes, Heximar Ointment is a prescription-only medicine (POM) in the United Kingdom and must be obtained through a qualified prescriber.

Will using Heximar Ointment affect blood test results?

Standard laboratory tests are not typically influenced by topical calcipotriol. However, if large skin areas are treated, calcium levels might be monitored.

Is there a risk of skin discoloration with long-term use?

Prolonged use on extensive areas can occasionally cause mild skin lightening or darkening. Report any noticeable changes to a healthcare provider.

Can I travel with Heximar Ointment in my carry-on luggage?

Yes, the tube can be carried in hand luggage. Keep it in its original packaging and ensure the cap is securely tightened to prevent leaks.

Are there any known drug interactions with common antihistamines?

No specific interactions between calcipotriol and over-the-counter antihistamines have been reported. Nonetheless, disclose all medications to your prescriber.

What is Heximar Ointment?

Heximar Ointment contains calcipotriol as its active ingredient. Calcipotriol is a synthetic analogue of vitamin D that belongs to the skin-care therapeutic class. The product is supplied in a plastic tube and is available in two tube sizes: 15 g and 30 g. In the United Kingdom Heximar Ointment is a prescription-only medicine (POM) regulated by the Medicines and Healthcare products Regulatory Agency (MHRA).

How Heximar Ointment Works in the Body

Calcipotriol binds to the vitamin D receptor (VDR) found in skin cells. Activation of this receptor modifies the expression of genes involved in cell growth and differentiation. By normalising keratinocyte proliferation and encouraging the maturation of skin cells, calcipotriol reduces the thick, scaly plaques that are characteristic of psoriasis. The effect typically becomes noticeable after several weeks of consistent use. Oral absorption from topical application is minimal, so systemic exposure is low.

Treating Plaque Psoriasis with Heximar Ointment

Heximar Ointment is approved in the UK for the topical treatment of plaque psoriasis in adults. The indication covers mild to moderate disease that is limited to body surface areas where an ointment can be applied. It is not intended for use on facial skin, intertriginous areas, or mucous membranes unless specifically directed by a specialist.

Typical patients are adults with chronic plaque psoriasis who have not responded adequately to emollients alone. Calcipotriol may be used as monotherapy or in combination with other topical agents such as corticosteroids, as directed by a clinician.

Off-Label and Investigational Applications

No robust peer-reviewed evidence currently supports off-label uses of calcipotriol in Heximar Ointment. Consequently, this section is omitted.

Who Should Use Heximar Ointment? Contraindications and Precautions

Absolute Contraindications

  • Known hypersensitivity to calcipotriol or any component of the ointment
  • Patients with hypercalcaemia or disorders of calcium metabolism

Relative Contraindications

  • Pregnant or lactating women (use only when the potential benefit outweighs risk)
  • Children under 18 years (safety not established for this age group)
  • Individuals with extensive skin breakdown where large surface areas would be treated

Special Populations

  • Pregnancy & Lactation: Calcipotriol crosses the placenta in animal studies; use only if clearly indicated.
  • Elderly: No dosage adjustment is required, but monitor for skin irritation.

If any of these conditions apply, a healthcare professional should evaluate suitability before prescribing Heximar Ointment.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Mild skin irritation at the application site
  • Dryness or peeling of the treated skin
  • Itching that resolves with continued use or reduced frequency

Serious Adverse Events

  • Hypercalcaemia (rare, usually with excessive use over large skin areas)
  • Severe allergic reactions such as erythema, swelling, or blistering

Drug Interactions

  • Systemic Vitamin D analogues (e.g., oral calcitriol) may increase the risk of hypercalcaemia; concurrent use should be avoided or closely monitored.
  • Topical corticosteroids used on the same area may alter local absorption; coordinate therapy with a prescriber.

Food and Lifestyle Interactions

  • No significant food-drug interactions are known for topical calcipotriol.
  • Sun exposure does not contraindicate use, but patients should apply sunscreen if they will be outdoors for prolonged periods.
  • There is no restriction on driving or operating machinery.

Patients should disclose all medications, supplements, and over-the-counter skin products to their healthcare provider before starting Heximar Ointment.

How to Take Heximar Ointment

  • Standard dosing: Apply a thin layer of the ointment to the affected skin once daily, preferably at night.
  • Amount per application: Use enough to cover the lesions without excess; the tube size (15 g or 30 g) is designed for typical daily use over several weeks.
  • Special populations: No dose reduction is required for elderly patients, but use the minimum amount needed to achieve improvement.
  • Application tips:
  • Wash hands before and after application.
  • Do not apply to broken skin, open wounds, or mucous membranes unless directed.
  • Missed dose: Apply the missed dose as soon as remembered, but do not double the next dose.
  • Overdose: Signs may include nausea, vomiting, excessive thirst, or confusion due to hypercalcaemia. Seek urgent medical attention; treatment focuses on supportive care and correction of calcium levels.
  • Discontinuation: Gradual tapering is not required, but abrupt cessation may lead to recurrence of plaques. Continue use as advised by the prescriber.

Monitoring and Follow-Up

Routine clinical review is recommended after 4-6 weeks of treatment to assess efficacy and skin tolerance. If large surface areas are being treated, periodic monitoring of serum calcium may be advised by the prescriber.

Storage and Handling

  • Store the tube at room temperature (15-25 °C) away from direct sunlight and moisture.
  • Keep the cap tightly closed when not in use.
  • Do not use the ointment after the expiry date printed on the packaging.
  • Dispose of empty tubes according to local pharmacy guidelines; keep out of reach of children.

Medication-Specific Glossary

Vitamin D Receptor (VDR)
A cellular protein that, when activated by calcipotriol, regulates gene expression involved in skin cell growth.
Hypercalcaemia
Elevated calcium levels in the blood, a rare but serious potential effect of excessive vitamin D analogue exposure.
Plaque Psoriasis
A chronic autoimmune skin condition characterized by raised, red, scaly patches.

Medical Disclaimer

This article provides educational information about Heximar Ointment and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Information for Heximar Ointment is sourced from established medical standards and updated frequently. It is provided for general guidance and should be confirmed with a healthcare professional before use.
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