Buy Cartia Xt
Cartia Xt

1.93
Cartia Xt (Diltiazem) is an extended-release calcium channel blocker used to treat high blood pressure and prevent chest pain. By relaxing blood vessels, it allows the heart to pump more efficiently with less effort. Cartia Xt provides a steady release of medication, ensuring consistent cardiovascular protection throughout the day.


Ingredient
Availability
In Stock
Delivery Time
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Diltiazem
Reference Brand
Adizem
Manufacturer
Actavis
Product Form
Extended-release capsule
Regulatory Classification
Rx
Primary Category
Blood Pressure Support, Heart Medication
Product Category
Cardiovascular system, Calcium channel blockers, Benzothiazepine derivatives
Pharmacological Class
Calcium channel blocker (Class III)
Manufacturer Description
A long-acting medication for high blood pressure and the prevention of chest pain (angina).
Mechanism of Action
Diltiazem relaxes the muscles of your heart and blood vessels. By doing so, it lowers blood pressure and reduces the workload on the heart, making it easier for the heart to pump blood and preventing chest pain.
Route of Administration
Oral
Onset Time
2-3 hours
Duration
24 hours
Contraindications
Second or third-degree heart block, Severe low blood pressure, Recent heart attack with lung congestion
Severe Adverse Events
Very slow heart rate, Fainting, Shortness of breath, Severe skin rash
Common Side Effects
Headache, Dizziness, Flushing
Uncommon Side Effects
Swelling of ankles or feet, Fatigue, Nausea
Drug Interactions
Beta-blockers, Digoxin, Statins, Cyclosporine
Pregnancy Safety Warnings
Not recommended during pregnancy.
Age Restrictions
Safety in children not established
Storage Guidelines
Store in a dry place at room temperature.
Related Products
Tiazac, Dilzem, Amlodipine

Cartia Xt FAQ

Can Cartia Xt be taken while traveling internationally?

Yes, Cartia Xt can be carried in hand luggage, but the pill should remain in its original packaging with a label showing the patient's name and dosage. Some countries may require a prescription copy; it's advisable to carry a doctor's note.

Will Cartia Xt affect drug testing for employment or sports?

Diltiazem is not a prohibited substance in standard drug-testing panels for workplace or sporting contexts. However, athletes should review the specific rules of their governing body.

What does the imprint on a Cartia Xt pill look like?

Cartia Xt 180 mg tablets typically bear the imprint “CXT 180” on one side, with a white to off-white color and a smooth coating.

Are there differences between Cartia Xt and other diltiazem brands?

Cartia Xt is an extended-release formulation delivering 180 mg over 24 hours, whereas immediate-release diltiazem tablets (e.g., Cardizem) require multiple daily doses. The pharmacokinetic profile and dosing frequency are the primary distinctions.

Can I drink coffee or tea with Cartia Xt?

Caffeine does not significantly interact with diltiazem, but large amounts of caffeine may increase heart rate, partially offsetting the drug’s effect. Moderation is recommended.

Is Cartia Xt safe for pilots or drivers?

If Cartia Xt causes dizziness or significant blood pressure lowering, it may impair driving or cockpit duties. The UK Civil Aviation Authority advises pilots to be assessed for fitness to fly after initiating any new cardiovascular medication.

How long does Cartia Xt remain stable after opening the bottle?

The tablets remain stable for the duration indicated on the expiry label, provided they are stored as directed. No special precautions are needed after opening the container.

What should I do if I develop ankle swelling while on Cartia Xt?

Peripheral edema is a known side effect. Patients should report the swelling to their prescriber, who may adjust the dose, switch to an alternative therapy, or add a diuretic if appropriate.

Does Cartia Xt have any impact on cholesterol levels?

Diltiazem does not directly affect lipid metabolism; it neither raises nor lowers cholesterol. Patients on Cartia Xt should continue routine cholesterol monitoring as part of overall cardiovascular care.

Are there any cost-saving programs for Cartia Xt in the UK?

NHS prescriptions for Cartia Xt are subject to standard NHS pricing and may be eligible for prescription prepayment certificates or low-income schemes. Patients should consult their pharmacy for details.

What is Cartia Xt?

Cartia Xt is a prescription medication that contains the active ingredient diltiazem. It is formulated as a 180 mg extended-release pill used to treat conditions within the Heart & Blood Pressure therapeutic area. In the United Kingdom, Cartia Xt is regulated by the Medicines and Healthcare products Regulatory Agency (MHRA) and is available only with a valid prescription.

How Cartia Xt Works in the Body

Diltiazem belongs to the class of drugs known as calcium-channel blockers (specifically, a non-dihydropyridine agent). It inhibits the influx of calcium ions through L-type calcium channels in cardiac and vascular smooth muscle. By doing so, it:

  • Reduces the contractility of the heart (negative inotropy) and slows conduction through the atrioventricular (AV) node (negative dromotropy).
  • Promotes relaxation of arterial smooth muscle, leading to vasodilation and lower blood pressure.

The extended-release formulation allows the drug to be absorbed gradually, providing a steady therapeutic effect over 24 hours. Onset of action typically occurs within 2 hours, with peak plasma concentrations reached around 6-8 hours after ingestion. The duration of effect matches the once-daily dosing schedule.

Conditions Treated by Cartia Xt

Cartia Xt is indicated in the UK for:

  • Hypertension (high blood pressure) when monotherapy or combination therapy is required.
  • Chronic stable angina (chest pain due to reduced coronary blood flow).
  • Rate control in atrial fibrillation or atrial flutter, where slowing the ventricular response is needed.

These approvals are based on clinical trials demonstrating that diltiazem effectively lowers blood pressure, reduces angina episodes, and controls heart rate without compromising myocardial oxygen demand.

Who Should Not Use Cartia Xt?

Absolute Contraindications

  • Known hypersensitivity to diltiazem or any component of the formulation.
  • Second- or third-degree AV block without a functioning pacemaker.
  • Sick sinus syndrome without a pacemaker.
  • Severe hypotension (systolic < 90 mmHg).
  • Cardiogenic shock or acute myocardial infarction with pulmonary edema.

Relative Contraindications

  • Moderate to severe hepatic impairment (dose adjustment may be required).
  • Congestive heart failure of New York Heart Association (NYHA) class III-IV.
  • Pregnancy (Category C - use only if potential benefit justifies the risk).
  • Breast-feeding - diltiazem is excreted in milk; caution advised.

Patients with any of the above conditions should discuss alternative therapies with their prescriber.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Headache
  • Flushing or warmth sensation
  • Dizziness or light-headedness
  • Peripheral edema (especially of the ankles)
  • Constipation

These effects are usually mild and may improve with continued therapy. If they persist or worsen, patients should contact their healthcare professional.

Serious Adverse Events

  • Marked bradycardia (heart rate < 50 bpm)
  • Advanced AV block (second- or third-degree)
  • Severe hypotension (symptomatic)
  • Hepatic dysfunction (elevated transaminases)
  • Heart failure exacerbation

Any of these symptoms warrant immediate medical assessment. Cartia Xt carries a black-box warning for severe bradycardia and AV block in the UK product information.

Drug Interactions

  • Major: Strong CYP3A4 inhibitors (e.g., clarithromycin, ketoconazole, ritonavir) can increase diltiazem plasma levels, raising the risk of bradycardia and hypotension.
  • Moderate: Beta-blockers, digoxin, and other calcium-channel blockers may have additive effects on heart rate and conduction; dose adjustments or close monitoring are advised.
  • Moderate: Quinidine, amiodarone, and certain anti-arrhythmic agents can increase diltiazem concentrations.
  • Lifestyle: Grapefruit juice can inhibit CYP3A4 metabolism, leading to higher diltiazem exposure.

Patients should provide a full list of current medicines, over-the-counter products, and herbal supplements to their prescriber.

Food and Lifestyle Interactions

  • Cartia Xt may be taken with or without food; however, swallowing the pill with a glass of water and a light breakfast can reduce the chance of gastrointestinal irritation.
  • Alcohol can exacerbate vasodilatory effects, potentially causing dizziness or hypotension.
  • Drowsiness may affect the ability to operate machinery or drive; patients should assess their own response before engaging in such activities.

How to Take Cartia Xt

  • Standard dosing: One 180 mg extended-release pill taken once daily, preferably in the morning with a glass of water.

  • Special populations:

  • Renal impairment: No dose adjustment is typically required unless severe.

  • Hepatic impairment: Start with a lower dose (e.g., 120 mg) and titrate cautiously.

  • Elderly: Begin with the lowest effective dose and monitor heart rate and blood pressure closely.

  • Administration notes: Do not split, chew, or crush the capsule - it is designed to release the drug slowly. If a dose is missed, take it as soon as remembered unless it is close to the next scheduled dose; do not double-dose.

  • Overdose: Symptoms may include severe hypotension, bradycardia, and heart block. Seek emergency medical care; treatment focuses on supportive measures and, if needed, intravenous calcium gluconate.

  • Discontinuation: Sudden cessation is generally safe, but patients with angina should be monitored for rebound chest pain. Tapering is rarely required for the extended-release formulation.

Monitoring and Follow-Up

  • Blood pressure should be measured before initiation and then periodically (e.g., after 2-4 weeks, then quarterly).
  • Heart rate and electrocardiogram (ECG) are recommended to detect bradycardia or conduction abnormalities, especially after dose changes.
  • Liver function tests are advisable at baseline and during long-term therapy in patients with hepatic disease.

Patients should report any new symptoms such as faintness, palpitations, or swelling promptly.

Storage and Handling

  • Store Cartia Xt at room temperature (below 30 °C), protected from moisture and direct sunlight.
  • Keep the medication out of reach of children and pets.
  • Do not use beyond the expiry date printed on the packaging.
  • Unused tablets should be disposed of via a pharmacy take-back scheme or according to local waste-medicine guidelines.

Medication-Specific Glossary

Calcium-Channel Blocker
A class of drugs that inhibit calcium entry into cardiac and vascular smooth-muscle cells, leading to reduced contractility and vasodilation.
AV Node
The atrioventricular node, a key electrical relay between the atria and ventricles; slowing its conduction reduces heart rate.
Extended-Release
A formulation designed to release the active ingredient gradually over an extended period, allowing once-daily dosing.

Medical Disclaimer

This article provides educational information about Cartia Xt and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Information for Cartia Xt is sourced from established medical standards and updated frequently. It is provided for general guidance and should be confirmed with a healthcare professional before use.
Categories
Hoe kunt u Spierontspanners & Ontstekingsremmers veilig aanschaffen - Feldene zalf tabletten Order medications for Viral Infection Treatment Hong Kong: - Buy Harvoni Hong Kong