Mirtazapine is a medication primarily used for the treatment of major depressive disorder and is also sometimes prescribed for other conditions such as anxiety, PTSD, and OCD. It works by increasing the levels of serotonin and norepinephrine, which are natural substances in the brain that help maintain mental balance.

Mirtazapine FAQ


What is Mirtazapine used for?

Mirtazapine is primarily used in the treatment of major depressive disorder. It may also be prescribed off-label for other conditions like anxiety, PTSD, and OCD.

How does Mirtazapine work?

Mirtazapine works by increasing the levels of neurotransmitters such as serotonin and norepinephrine in the brain, which help regulate mood.

What are the common side effects of Mirtazapine?

Common side effects may include drowsiness, increased appetite, weight gain, and dry mouth. However, not everyone will experience these side effects.

Can I buy Mirtazapine online without a prescription?

No, you cannot legally buy Mirtazapine in the UK without a prescription from a qualified healthcare professional.

How long does it take for Mirtazapine to start working?

It can take several weeks for Mirtazapine to have a noticeable effect. It's important to continue taking the medication as prescribed, even if you don't feel any immediate improvement.

Is Mirtazapine safe to take during pregnancy?

It's important to consult with a healthcare professional if you are pregnant or planning to become pregnant before taking Mirtazapine, as the risks and benefits need to be carefully considered.

How is Mirtazapine different from other antidepressants?

Mirtazapine has a unique mechanism of action compared to some other antidepressants, as it not only increases serotonin levels but also affects norepinephrine and other neurotransmitters.

Can Mirtazapine cause withdrawal symptoms?

Stopping Mirtazapine suddenly may lead to withdrawal symptoms such as dizziness, irritability, and flu-like symptoms. It's important to gradually reduce the dosage under medical guidance.

What should I do if I miss a dose of Mirtazapine?

If you forget to take your dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and take your next dose as scheduled.

Is it safe to drink alcohol while taking Mirtazapine?

Drinking alcohol may enhance the drowsiness caused by Mirtazapine. It's best to consult with your healthcare provider about the potential risks of combining alcohol with this medication.

Can Mirtazapine cause weight gain?

Some people may experience increased appetite and weight gain while taking Mirtazapine. This effect can vary from person to person.

What is the typical starting dosage of Mirtazapine?

The usual starting dose for Mirtazapine is 15mg taken once daily at bedtime. However, the dosage may vary based on individual factors and should be determined by a healthcare professional.

Is Mirtazapine addictive?

Mirtazapine is not considered to be addictive. It does not produce the same effects as drugs that are commonly associated with addiction.

Can Mirtazapine be taken with other medications?

It's important to inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking before starting Mirtazapine, as certain combinations can have potential interactions.

How long should I continue taking Mirtazapine?

The duration of Mirtazapine treatment should be determined by your healthcare provider. It's important not to discontinue the medication without consulting with them first, even if you start feeling better.

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Information provided by Maryam Abdullahi-Mahdi. Reviewed by Prof. Vijay Sangar