Cilostazol Medications

Cilostazol works by dilating arteries and preventing platelets from sticking together, which improves circulation in the limbs. It is primarily indicated for the treatment of intermittent claudication and improving walking distances. It is a critical component in trusted, affordable generic medications for circulatory health. Our platform facilitates easy and secure access to high-quality treatments containing Cilostazol for patients throughout the UK.

Pletal

Heart & Blood Pressure

50|100mg

0.83 / tablet
Buy

Cilostazol

Heart & Blood Pressure

50|100mg

0.83 / tablet
Buy

Cilostazol Info

What is Cilostazol?

Cilostazol belongs to a class of medicines called phosphodiesterase-3 inhibitors. It works mainly as a vasodilator-helping blood vessels to relax-and also limits how easily platelets stick together. In the UK, cilostazol is used in medicines such as Pletal and generic Cilostazol tablets.

Medications that contain Cilostazol

Both the brand-named product Pletal and the generic version are supplied as oral tablets. They are usually available in strengths of 50 mg and 100 mg. While Pletal is the most well-known name on pharmacy shelves, the same active ingredient can be found in other branded or hospital-supply tablets that may be listed simply as “Cilostazol.” All of these products share the same core ingredient but may differ in shape, colour, or additional inactive substances.

What does Cilostazol treat?

Cilostazol is primarily prescribed for:

  • Intermittent claudication - pain or cramping in the legs that occurs during walking because of reduced blood flow in peripheral arteries.
  • Peripheral arterial disease (PAD) - when arteries outside the heart and brain become narrowed, limiting circulation to the lower limbs.

These medicines help improve walking distance by widening blood vessels and reducing platelet clumping, making it easier for oxygen-rich blood to reach leg muscles. They are generally intended for adults who can walk on their own and are not used as a first-line treatment for heart attacks or strokes.

How Cilostazol works

Cilostazol gently relaxes the smooth muscle in blood-vessel walls, which widens the vessels and boosts blood flow to the legs. At the same time, it makes platelets less likely to stick together, lowering the chance of tiny clots that could block those vessels. This dual action can start to improve walking ability within a few weeks of regular use, although full benefit may develop over a longer period.

Safety information

Common side effects

Most people notice mild, short-lasting effects such as:

  • Headache
  • Diarrhoea or stomach upset
  • Dizziness or light-headed feeling
  • Palpitations (a rapid or fluttering heartbeat)

These symptoms usually lessen as the body gets used to the medicine.

Serious reactions

Rare but important signs that need urgent medical attention include:

  • Chest pain or tightness
  • Severe, sudden shortness of breath
  • Swelling of the face, lips, or tongue
  • Skin rash that spreads quickly or blisters

If any of these occur, seek help immediately.

Who should be cautious

Cilostazol is not recommended for people with:

  • Active heart failure or recent heart attack
  • Recent stroke or bleeding in the brain
  • Severe liver disease
  • Known allergy to cilostazol or any tablet ingredient

Pregnant or breastfeeding individuals should avoid it unless a specialist advises otherwise.

Interaction awareness

Cilostazol can affect the action of other medicines, especially:

  • Anticoagulants such as warfarin - may increase bleeding risk
  • Other drugs that influence platelet function (e.g., aspirin, clopidogrel)
  • Certain antibiotics and antifungal agents that change how the liver processes the drug

Alcohol can heighten dizziness, so it is worth being cautious when drinking. For a full list of possible interactions, refer to the individual product’s information leaflets.

What to know before using

  • Keep tablets in their original container, stored below 25 °C and away from moisture.
  • The length of treatment varies; some people use it for a few months, others for longer periods, depending on their doctor’s plan.
  • Always follow the specific instructions that come with the product you have, as formulations and strengths can differ.

For detailed dosing and administration, see the information supplied with your particular medication.

Key terms

Phosphodiesterase-3 inhibitor: a type of drug that relaxes blood vessels and reduces platelet clumping.

Intermittent claudication: leg pain that appears during walking because of insufficient blood flow.

Platelet aggregation: the process by which platelets stick together to form a clot.

Information disclaimer

This article provides general educational information about cilostazol as an active substance used in various medicines. It is intended to help patients understand the ingredient and the conditions it may be used for. It is not a substitute for professional medical advice or the specific instructions that accompany individual products. Medicines containing cilostazol can differ in formulation, strength, and usage directions. Always refer to the labeling of your particular medication and follow the guidance of your healthcare provider for complete information on proper use, dosage, and safety.

Information regarding Cilostazol is compiled from recognised clinical guides and reviewed periodically. This is for general reference; always check with a doctor or healthcare provider before starting any treatment.
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